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Contraception clinical trials

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NCT ID: NCT00482963 Completed - HIV Infections Clinical Trials

A Study of the Drug Interactions Between a Hormonal Emergency Contraception and an HIV Medication

Start date: May 2007
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine if blood levels of the hormonal emergency contraceptive agent, Plan B, are altered by concomitant use with the HIV medication, efavirenz.

NCT ID: NCT00477633 Completed - Contraception Clinical Trials

Study of Safety and Efficacy of an Oral Contraceptive

Start date: June 2007
Phase: Phase 3
Study type: Interventional

This is a non-comparative study. the primary objective of the study is to assess the efficacy of a low dose oral contraceptive in the prevention of pregnancy. The secondary objectives are to assess the incidence of intracyclic bleeding; and to assess the safety and tolerability of the product.

NCT ID: NCT00476021 Completed - Contraception Clinical Trials

Postplacental or Delayed Insertion of the Levonorgestrel-releasing Intrauterine Device (IUD) After Vaginal Delivery

POPI
Start date: May 2007
Phase: N/A
Study type: Interventional

This study is a randomized controlled trial comparing 6 month usage rates of the levonorgestrel-releasing intrauterine device (LNG-IUD) when inserted postplacentally after vaginal delivery or delayed placement at 6-8 weeks postpartum. Given the high rate of unintended pregnancy in the United States, particularly in postpartum women, there is a need for reliable, effective, long-term contraception such as the IUD in postpartum women. Postplacental insertion of intrauterine contraception would help to address this need. The primary hypothesis of this study is that use of the LNG-IUD at 6 months after vaginal delivery will be higher in women who have immediate postplacental insertion as compared to delayed insertion 6-8 weeks following delivery.

NCT ID: NCT00471185 Completed - Contraception Clinical Trials

ACY-6 Oral Administration of Acyline

ACY-6
Start date: June 2007
Phase: Phase 1
Study type: Interventional

In this study, we propose oral dosing of GIPET enhanced oral acyline (MER-104) to determine if this potentially useful compound is safe and effective at suppression of gonadotropins after oral dosing in man. Hypothesis: A single dose of Acyline will suppress gonadotropins, and testosterone, estradiol and dihydrotestosterone (DHT) for 24 hours in man, and the magnitude and duration of the suppression will increase with increasing doses of Acyline.

NCT ID: NCT00468481 Completed - Contraception Clinical Trials

Efficacy and Safety Study for an Oral Contraceptive Containing Folate

Start date: April 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether the study drug is safe and effective

NCT ID: NCT00456924 Completed - Contraception Clinical Trials

Low Dose Continuous Administration of the Progesterone Receptor Modulator VA2914

Start date: January 2004
Phase: Phase 2
Study type: Interventional

The purpose of the present study is to evaluate continuous administration of low doses of VA2914 for potential contraceptive activity and effects on the menstrual cycle and steroid hormone parameters.

NCT ID: NCT00455156 Completed - Contraception Clinical Trials

Study of the Safety, Efficacy and Cycle Control of a Contraceptive Vaginal Ring

Start date: December 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the one-year data on the contraceptive efficacy and safety of the 150/15 NES/EE CVR as the basis for regulatory approvals of this CVR as a new delivery system for contraception.

NCT ID: NCT00436306 Completed - Pregnancy Clinical Trials

Stage Matched Intervention to Increase Dual Method Use

PROTECT
Start date: October 1999
Phase: Phase 4
Study type: Interventional

The primary purpose of Project PROTECT was to evaluate two different intervention approaches that encourage young women to use dual methods of contraception. The individualized intervention is a computer assisted, fully-tailored, interactive intervention based on the transtheoretical model of behavior change. This intervention was compared to an enhanced standard care intervention that provided computer-based, non-tailored information and advice regarding the use of contraceptive methods. The two primary outcomes of this trial include: 1) a behavioral outcome: the reported use of dual methods of contraception; and 2) a biological outcome: an incident or recurrent STI or unintended pregnancy. The hypotheses of this trial were: 1) the individualized intervention will result in a greater increase in dual contraceptive use than the standard care approach; and 2) the individualized intervention would result in greater protection against incident or recurrent cases of sexually transmitted infections and unplanned pregnancies.

NCT ID: NCT00413062 Completed - Contraception Clinical Trials

Efficacy and Safety Study of the Combined Oral Contraceptive NOMAC-E2 Compared to a COC Containing DRSP/EE (292002)(P05722)

Start date: June 2006
Phase: Phase 3
Study type: Interventional

The primary purpose of this study is to assess contraceptive efficacy, vaginal bleeding patterns (cycle control), general safety and acceptability of the nomegestrol acetate-estradiol (NOMAC-E2) combined oral contraceptive (COC) in a large group of women aged 18-50 years.

NCT ID: NCT00403793 Completed - Contraception Clinical Trials

Hormonal Contraception in Healthy Young Men (P42306)(COMPLETED)(P06057)

Start date: October 2003
Phase: Phase 2
Study type: Interventional

Male volunteers receive a new hormonal contraceptive consisting of an implant releasing a hormone and hormone injections in order to investigate the suppressive effect on sperm production and reversibility of sperm production after end of treatment.