Decline in Renal Concentration Ability in Lithium Treated Patients

Status Not yet recruiting

Clinical Trial Summary

Lithium therapy is cornerstone in therapy of bipolar disorders. A well known side-effect of lithium therapy is a urinary concentration defect which manifests in it's most severe form as nephrogenic diabetes insipidus. The development of urinary concentration defects and its progression to nephrogenic diabetes insipidus in the population of lithium treated patients is unknown and therefore this study aims to evaluate the decline of urinary concentration defects in a Dutch population of lithium treated patients. In this prospective cohort study, 51 participants treated with lithium at Canisius Wilhelmina Hospital, Nijmegen and included in the previous study in 2012 will be approached to undergo a follow-up dDAVP-test.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05307042
Study type	Observational
Source	Radboud University Medical Center
Contact	M.J. van der Aa
Phone	(073) 553 30 71
Email	merel.vanderaa@radboudumc.nl
Status	Not yet recruiting
Phase
Start date	May 2022
Completion date	December 2022

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