Cognitive Impairment Clinical Trial
Official title:
Cognitive Function Before and After Opioid Reduction in Patients With Chronic Pain A Prospective Cohort Study
This study aims to investigate the cognitive function of patients in the opioid reduction
programme at the multidisciplinary pain centre at Zealand University Hospital Køge.
The patients will be tested before, halfway through, and after the programme.
The number of patients with chronic non-malignant pain is high and constant. An estimated
3-5% of the population use opioids daily. These patients have a lower quality of life and a
higher use of healthcare services.
This leads to enormous costs, both human and economic. Many patients lose their ability to
work, not only because of the pain, but also because of their treatment.
For a long period, opioids have been prescribed for chronic pain, even though the evidence is
scarce.
A rising conscience about opioid use is on the way, and now, there is a tendency to reduce,
rather than increase opioids.
The reasons are many: Constipation, inability to drive, a sense of drowsiness and no relief
of pain, just to name a few. Furthermore, opioids may have decreased effect over time or may
even lead to higher levels of pain.
Many patients are at first reluctant to start the reduction programme. Mostly because the
patients may not be aware of the effects, the drugs are having on them. Many patients value
their opioid treatment as positive and necessary, in spite of the many adverse effects.
The investigators wanted to test the cognitive function of patients before, during and after
opioid reduction. The results can be used to help patients understand the deleterious effects
of high opioid usage, and can also be used to motivate the individual patient along the way.
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