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Cognition Disorders clinical trials

View clinical trials related to Cognition Disorders.

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NCT ID: NCT03120741 Not yet recruiting - Clinical trials for Mild Cognitive Impairment, Dementia

Dementia Patient's Behavior Evaluation Using Noninvasive Ambient Sensor

Start date: May 2017
Phase: N/A
Study type: Observational

This study is an observational study that uses daily activity and environmental sensing techniques to establish behavioral models of early dementia patients and cognitive healthy function to assess their daily behavior and determine their activities. Specifically, the team will collect information on a number of wireless sensors for dementia, mild cognitive impairment and healthy elderly residents, and use special mathematical models to establish the behavior of the two groups of subjects Model. The model will be developed a reliable algorithm to assess health risk of the subjects.

NCT ID: NCT03087435 Not yet recruiting - Depression Clinical Trials

Well-Being in Medical Residents in the HIBA

Start date: December 2019
Phase:
Study type: Observational

It is necessary and important to design tools to evaluate a central aspect of medical residents formation. The research group has been working with resident well-being since a few years in order to improve the global quality of the education and working environment. The investigators present a plan to develop and validate a tool to assess residents well-being. A tool designed with this characteristics would be of much importance to monitored as a security event, managed and actively promoted well being in residents.

NCT ID: NCT03030365 Not yet recruiting - Alzheimer Disease Clinical Trials

Orientation in AD Patients: PET-MR Study

Start date: February 15, 2017
Phase: N/A
Study type: Observational

Despite the high prevalence of Alzheimer's disease (AD), its underlying mechanisms remain poorly understood. An emerging body of evidence supports disorientation as an early marker for AD-related neurodegeneration. In this study we intend to collect, coregister and analyze Positron Emission Tomography (PET) and , functional and structural magnetic resonance imaging (MRI, fMRI) data from AD-spectrum patients to establish orientation as core disturbance in AD.

NCT ID: NCT02987842 Not yet recruiting - Alzheimer Disease Clinical Trials

Neurofeedback as a Novel Treatment for Mild Cognitive Impairment & Early Alzheimer's Disease

Start date: December 2016
Phase: N/A
Study type: Interventional

This study protocol proposes an EEG based neurofeedback (EEG-NFB) technique to upregulate the posterior cingulate cortex (PCC) in patients suffering from mild cognitive impairment (MCI) and early Alzheimer's disease (AD). EEG-NFB has been successfully used as a clinical tool for over 40 years. It is based on electrical activity measured near the surface of the brain using EEG and fed back to the patient within half a second. MCI is a clinical condition considered as a precursor of AD. NFB appears to be a promising approach to treat MCI, since it has been shown to be able to induce changes in brain plasticity. This research focuses on the PCC, which has been reported to be implicated in MCI, and due to its location (proximity to the surface) accessible by means of EEG- NFB. A preliminary research in MCI patients, conducted at our lab showed the lower the memory score was at the beginning of the training, the better a subject managed to improve later on. The investigators therefore presume that patients with early Alzheimer's disease, whose cognitive ability is more affected compared to MCI, may benefit from EEG-NFB as well, and maybe to a larger extent compared to MCI.

NCT ID: NCT02763397 Not yet recruiting - Cognitive Deficit Clinical Trials

Deep Brain Stimulation (DBS) of the Nucleus Basalis of Meynert (NbM) in Patients With Parkinson's Disease

Start date: May 2016
Phase: N/A
Study type: Interventional

The existing DBS setting in patients with DBS of the globus pallidus interna (GPi), which aims to treat motor symptoms by a high-frequency stimulation, will be temporarily reprogramed to stimulate the NbM at a low frequency using the distal electrodes positioned in the vicinity of the NBM. This study aims to investigate the neuropsychological effect of low frequency stimulation of the nucleus basalis of Meynert (NBM) in advanced Parkinson's disease (PD) patients, who were previously treated with deep brain stimulation (DBS) of the globus pallidus interna (GPi).

NCT ID: NCT02745132 Not yet recruiting - Hepatitis C Clinical Trials

Cognitive Impairments in Chronic Hepatitis C Patients and Potential Reversibility With New Agents (CICHepC)

CICHepC
Start date: June 2016
Phase: Phase 4
Study type: Interventional

The overall aim of this study is to evaluate the prevalence of cognitive impairments and brain anomalies in Chronic Hepatitis C infected individuals and to investigate likely changes in cognition and brain structure and function after treatment with Direct-acting Antivirals (DAAs).

NCT ID: NCT02741804 Not yet recruiting - Clinical trials for Mild Cognitive Impairment

Lifestyle Intervention Program for Cognitive Impairment

Start date: May 2016
Phase: N/A
Study type: Interventional

The purpose of the Lifestyle Intervention Study is to investigate the influence of a micronutrient supplement in combination with a comprehensive lifestyle intervention program on retinal amyloid, among patients with Mild Cognitive Impairment (MCI). Patients will be placed on supplement or placebo throughout their 18-month study participation. Patients will also be given lifestyle training on nutrition, physical activity, cognitive and social activity, meditation and sleep, which have all been proven to positively affect cognition over time. Throughout their participation, patients' cognitive functioning will be monitored with comprehensive imaging, neuropsychological testing, blood testing and study compliance.

NCT ID: NCT02393222 Not yet recruiting - Stroke Clinical Trials

Assessing Cognitive fUnction and MEasuring the Cerebral circulatioN on HaemoDialysis

ACUMEN-HD
Start date: March 2015
Phase: N/A
Study type: Observational

Stroke disease and cognitive impairment are common in patients established on haemodialysis (HD) for end-stage renal disease (ESRD). Further, initiation of HD appears to transiently increase the risk of stroke. The mechanism by which this occurs is not known. Using ultrasound, patient questionnaires and brain MRI our study will observe changes in cognition and cerebral blood flow whilst receiving HD compared to a non-dialysis day. Transient clinical and ultrasound alterations will be correlated to radiographic changes in cerebral perfusion and structure on MRI to determine the underlying mechanism for the increased stroke risk. The investigators will observe this effect in the immediate and longer term (12 months observation). A greater understanding will allow development of effective preventive strategies.

NCT ID: NCT02366442 Not yet recruiting - Clinical trials for Traumatic Brain Injury

Exploring Relationships Among Balance Performance, Cognitive Dysfunction, Affective Dysregulation, and Community Integration in Veterans With Traumatic Brain Injury (TBI)

Start date: February 2015
Phase: N/A
Study type: Observational

The overarching goal of the proposed study, named SYNERGY, is to explore relationships among balance performance, cognitive function, affective dysregulation, as they relate to the community re-integration in Veterans with TBI. The SYNERGY study findings can aid in the development of a better outcome models for the clinicians in facilitating effective community re-integration in Veterans with TBI

NCT ID: NCT02332525 Not yet recruiting - Clinical trials for Mild Cognitive Impairment

The Influence of Oral Vibrational Stimulation on Cognitive Function of Elderly Individuals

OVSCF
Start date: January 2015
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to investigate the effect of oral vibratory stimulus on the brain activity and cognitive function of elderly people with non-dementia subjects (cognitive normal, mild cognitive impairment)