Cocaine Dependence Clinical Trial
— ETDDThis study tests the effectiveness of two 24 month, telephone-based adaptive continuing care interventions for patients with cocaine dependence. The two interventions are predicted to produce better drug use outcomes than standard care. Furthermore, the intervention that also includes monetary incentives for continued participation is hypothesized to produce better retention and drug use outcomes than the intervention without incentives. Economic analyses will determine the cost-effectiveness and benefit-cost of the interventions relative to standard care, and to each other.
Status | Recruiting |
Enrollment | 340 |
Est. completion date | May 2011 |
Est. primary completion date | |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years to 75 Years |
Eligibility |
Inclusion Criteria: - qualify for a DSM-IV lifetime diagnosis of cocaine dependence and cocaine use in 6 months prior to treatment; - initial engagement in IOP, as indicated by attendance at 4 or more sessions in the first two weeks of treatment; - 18 to 75 years of age; - willingness to be randomized and participate in research. - metropolitan area residents; - able to provide the name, verified telephone number, and address of at least one contact who can provide locator information on the patient during follow-up. Exclusion Criteria: - current psychotic disorder or evidence of dementia severe enough to prevent participation in outpatient treatment; - acute medical problem requiring immediate inpatient treatment; - current participation in methadone or other forms of DA treatment, other than IOP |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
United States | NorthEast Treatment Centers | Philadelphia | Pennsylvania |
United States | Presbyterian Hospital | Philadelphia | Pennsylvania |
Lead Sponsor | Collaborator |
---|---|
National Institute on Drug Abuse (NIDA) |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Abstinence from cocaine, alcohol, and other drugs. | within each 3 month segment of the follow-up | ||
Secondary | percent days cocaine use | within each 3 month segment of the follow-up |
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