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Clinical Trial Summary

In the United States, 1.5 million people abuse cocaine leading to a host of negative health and economic consequences, yet no FDA approved treatment exists. To develop effective treatments, the following must be considered: 1) do potential medications ameliorate brain disruptions associated with cocaine use? 2) are multiple, targeted treatments necessary? To meet these goals, innovative multi-modal neuroimaging will be used to determine whether rebalancing the serotonergic (5-HT) system reduces cocaine cue reactivity, impulsivity, and normalizes related neurochemistry and brain connectivity.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03266939
Study type Interventional
Source Mclean Hospital
Contact Amy Janes, PhD
Phone (617)855-3244
Email ajanes@mclean.harvard.edu
Status Not yet recruiting
Phase Phase 1
Start date September 2018
Completion date December 2018

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