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Clinical Trial Summary

The objective of the investigators study is to assess conventional repetitive transcranial magnetic stimulation (rTMS) in patients with chronic severe tinnitus. A randomized, double-blind, sham-controlled procedure, with four increasing levels of magnetic "pseudo-dose" has been designed, in order to characterize the effectiveness of rTMS while controlling its safety and tolerability. By combining various rTMS protocols with a twelve-month follow-up, and using an effect modeling, the study aims at: (i) specify the effective values of rTMS parameters, with an adequate tolerance; (ii) determine the expected benefit and the persistence of effect; (iii) assess the practical feasibility of this kind of therapeutic management.


Clinical Trial Description

n/a


Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Outcomes Assessor), Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT01407133
Study type Interventional
Source Hospices Civils de Lyon
Contact
Status Completed
Phase Phase 1/Phase 2
Start date May 2005
Completion date September 2009

See also
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Completed NCT01907022 - Combined rTMS and Relaxation in Chronic Tinnitus N/A
Completed NCT01663324 - rTMS for the Treatment of Chronic Tinnitus: Optimization by Simulation of the Cortical Tinnitus Network N/A
Completed NCT01663311 - Repetitive Transcranial Magnetic Stimulation With Double Cone Coil in Chronic Tinnitus N/A
Completed NCT02653547 - Influence of Treatment Duration and Stimulation Frequency on rTMS in Chronic Tinnitus N/A
Completed NCT02199106 - Effectiveness of Neuronavigated Continuous Theta Burst Stimulation of the Left Heschl's Gyrus in Chronic Tinnitus N/A
Recruiting NCT03657615 - Hearing Aid Impact on Chronic Tinnitus Patients Evaluated by Resting State PET. N/A
Completed NCT02306447 - Combined Transcranial and Peripheral Muscle Magnetic Stimulation in Chronic Tinnitus N/A