Comparison of PRP & DFDBA vs. DFDBA in Intrabony Periodontal Defects

Status Completed

Clinical Trial Summary

The purpose of this clinical trial is to compare the results in subjects with periodontitis using subjects own blood - Platelet-rich plasma (PRP) combined with bone graft material, namely, Demineralized Freeze - Dried Bone Allograft (DFDBA) or DFDBA alone in the treatment of bone defects around the teeth.

Clinical Trial Description

After being informed about the study and potential risks, 13 patients giving written informed consent and who meet the eligibility requirements were randomly allocated in a single blind manner (participants) to test group (PRP combined with DFDBA) or control group (DFDBA). 33 sites (18 test, 15 control unpaired defects) were treated - 1) to investigate the possible additional effects of PRP when combined with DFDBA, and 2) to compare the clinical and radiographic outcomes obtained in test and control groups,12 months post - operatively. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05886699
Study type	Interventional
Source	Government Dental College and Hospital, India
Contact
Status	Completed
Phase	N/A
Start date	January 2012
Completion date	December 2013

View Details

See also
Status	Clinical Trial	Phase
Not yet recruiting	`NCT06400069` - Role of NLRP6 in Chronic Periodontitis
Completed	`NCT05231096` - Comparison of the Effect of Gingival Massage of Aloe-vera Gel and Sidr Honey on Chronic Periodontitis	N/A
Completed	`NCT03203746` - Gingival Crevicular Fluid Levels of Protein Carbonyl Following the Use of Lycopene in Chronic Periodontitis	Phase 1/Phase 2
Active, not recruiting	`NCT03354338` - Amoxicillin to Prevent Bacteria and Inflammatory Biomarkers After Intensive Periodontal Therapy	Phase 2
Completed	`NCT02516111` - Comparison of Autologous PRF, 1% Alendronate and 1.2% Atorvastatin Gel in Chronic Periodontitis Treatment	Phase 2/Phase 3
Completed	`NCT02174146` - Leptin and Visfatin in Diabetic Patients With Periodontitis Before and After Periodontal Therapy	N/A
Terminated	`NCT02568163` - Influence of Stress on Non Surgical Periodontal Treatment	N/A
Completed	`NCT02430519` - Benefits of Platelet Rich Fibrin In Mandibular Molar Furcation Defects	N/A
Completed	`NCT01438333` - Efficacy of INERSAN in Patients With Chronic Periodontitis as Adjunctive to Full Mouth Disinfection	N/A
Completed	`NCT01233765` - Analysis of Neutrophil Response in Chronic Periodontitis	N/A
Completed	`NCT02218515` - Treatment of Intrabony Periodontal Defects With Enamel Matrix Derivatives and Autogenous Bone Graft	Phase 4
Completed	`NCT02197260` - Antimicrobial Therapy as Adjunct to Periodontal Treatment: Effect of Timing	Phase 4
Not yet recruiting	`NCT03270280` - Comparison of Salivary Interleukin-1β and Matrix Metalloproteinase-8 Levels in Individuals With Chronic Periodontitis	Phase 2
Not yet recruiting	`NCT04026828` - Evaluation of Possible Genes in Periodontal Diseases by Genetic Methods
Completed	`NCT04697199` - The Adjunctive Effect of Probiotics to Non Surgical Treatment of Chronic Periodontitis	Phase 1
Completed	`NCT04643288` - Nanocrystalline Hydroxyapatite Bone Substitute for Treating Periodontal Intrabony Defects	N/A
Completed	`NCT03039244` - Evaluation of Antimicrobial Photodynamic Therapy as an Adjunct to Periodontal Treatment in Smokers	N/A
Completed	`NCT02898675` - Advantages of Autologous Platelet-Rich Fibrin Membrane on Growth Factor Levels and Periodontal Healing	N/A
Completed	`NCT02518152` - Platelet Rich Fibrin+1% Alendronate in Treatment of Chronic Periodontitis	Phase 2/Phase 3
Completed	`NCT02851823` - Combined Use of Er:YAG and Nd:YAG Laser	N/A