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Chronic Pain clinical trials

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NCT ID: NCT02666040 Active, not recruiting - Chronic Pain Clinical Trials

Study on Ultrapro vs Polypropylene: Early Results From a Multicentric Experience in Surgery for Hernia

SUPERMESH
Start date: November 2009
Phase: N/A
Study type: Interventional

With reference to inguinal hernia surgeries with prosthesis, the multicenter study aims to investigate the benefits in terms of incidence of pain and discomfort, improvement in the quality of life for the patient after the use of the newly introduced semi-absorbable prosthesis (ULTRAPRO® meshes) compared with the prosthesis of totally nonabsorbable material (conventional meshes in polypropylene "Prolene®"), and in terms of the costs for the hospital, the National Health System (NHS), and the society of associates for the use of the ULTRAPRO® in inguinal hernia surgeries.

NCT ID: NCT02660749 Active, not recruiting - Heart Surgery Clinical Trials

The Effect Of Tramadol, Metamizol and Dexketoprofen Combination On Chronic Pain Development After Heart Surgery

Start date: May 2015
Phase: N/A
Study type: Observational

Non Coronary Heart Surgery scheduled for the study , in patients with acute postoperative period Use of tramadol retard, metamizol and dekxketoprofen the effects on pain and character has been seen in the chronic phase targeted.

NCT ID: NCT02658474 Active, not recruiting - Chronic Pain Clinical Trials

Multidisciplinary Group Based Treatment of Patients With Chronic Pain

Start date: August 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether group based Acceptance and Commitment Therapy (ACT) at a university hospital clinic is superior to treatment in a primary care setting among patients with chronic pain. Hypothesis: i) A group based ACT treatment leads to less pain and greater Health Related Quality of Life (HRQOL) in patients with chronic pain than treatment in a primary care setting. ii) The improvement in pain and HRQOL is mediated through an increased degree of pain willingness and involvement in activities. iii) Improvement of pain and HRQOL after the two treatments is associated with demographic, psychosocial and somatic characteristics.

NCT ID: NCT02636972 Active, not recruiting - Chronic Pain Clinical Trials

The Progression From Dysmenorrhoea to Chronic Pelvic Pain

Start date: November 2014
Phase: N/A
Study type: Observational

This is a cross-sectional observational study. For participants resident in Adelaide, South Australia. The study consists of 3 visits to the Pain and Anaesthesia Research Clinic (PARC), within the Royal Adelaide Hospital (RAH). A total of 56 participants will be recruited for this study.

NCT ID: NCT02303847 Active, not recruiting - Chronic Pain Clinical Trials

Ultra-low Dose Oral Ketamine for Chronic Pain in the Primary Care Setting

Ketamine
Start date: November 2014
Phase: Phase 3
Study type: Interventional

This project is a pilot study to evaluate the analgesic and opioid-sparing effects of ketamine in an ultra-low dose oral formulation as a novel intervention for treatment of chronic non-cancer pain in opioid-tolerant patients in the primary care outpatient setting.

NCT ID: NCT02248363 Active, not recruiting - Chronic Pain Clinical Trials

Nationwide Evaluation of Multimodal Rehabilitation in Patients With Chronic Musculoskeletal Pain

Start date: September 2014
Phase:
Study type: Observational [Patient Registry]

Chronic pain is a common health problem that causes enormous social costs. A common method for treating patients with chronic pain problems are multimodal rehabilitation (MMR), which consists of a combination of physical exercise, cognitive behavioural therapy and work training coordinated in an interdisciplinary team. Our research aims to evaluate the effectiveness of MMR on health, quality of life, physical activity, return to work and health economics, with the long-term goal of developing MMR. We aim also to evaluate predictive factors for good and bad treatment outcomes in order to better adapt the MMR to the patient. The project is based on patient-reported data from the Swedish Quality Registry for Pain Rehabilitation, which routinely collects data from 40 (2017) Swedish specialist MMR clinics from all parts of the country. We expect increased knowledge of treatment effects and how MMR can be effectively adapted according to the patient's limitations and resources. Our project group is interdisciplinary and is active in nationwide research networks that focus on chronic pain and rehabilitation.

NCT ID: NCT02192398 Active, not recruiting - Chronic Pain Clinical Trials

Effect of Guanfacine on the Reversal of Opioid-induced Hyperalgesia (OIH)

Start date: September 2014
Phase: N/A
Study type: Interventional

Combination of guanfacine with opioid medication as a standard treatment for chronic pain.

NCT ID: NCT02117921 Active, not recruiting - Chronic Pain Clinical Trials

Mind Body Syndrome (MBS) Therapy for the Treatment of Chronic Pain

Start date: February 2014
Phase: N/A
Study type: Interventional

To determine if Mind Body Syndrome (MBS) therapy will reduce or eliminate pain in patients suffering from chronic pain syndromes without organic etiology.

NCT ID: NCT01994343 Active, not recruiting - Chronic Pain Clinical Trials

Pain in Women With Chronic Pelvic Pain

Start date: November 2013
Phase: N/A
Study type: Interventional

Chronic pelvis pain is very common between adult women. Significant progress is made in clarifying the multifactorial model of chronic pain pathogenesis, but a more complete assessment is important in order to improve the therapeutic approach. The purpose of this study is stablish a clinical and symptomatological profile of women with chronic pelvic pain.

NCT ID: NCT01967342 Active, not recruiting - Pain Clinical Trials

Literacy-Adapted Psychosocial Treatments for Chronic Pain --- "Learning About Mastering/My Pain"

LAMP
Start date: May 2013
Phase: N/A
Study type: Interventional

Chronic pain is a significant public health problem that affects over 116 million Americans, costs $600 billion annually, and is unequally borne by people in low-income brackets, especially ethnic minorities. Many individuals also have health literacy deficits (difficulty understanding their illness and difficulty navigating the health care system for treatment) putting them at a greater disadvantage. Treatment usually relies on expensive medical interventions that often have negative side-effects. Psychosocial treatments, like Pain Education and Cognitive-Behavioral Therapy (CBT), show promise, but are usually unavailable. Clinicians are poorly equipped to provide psychosocial treatments to patients with low health literacy. CBT has not been adapted and supported for use in individuals with low health literacy, and even educational materials are often poorly adapted for their needs. To address this problem, the PI completed a small trial showing benefits from health literacy-adapted pain education and CBT groups for chronic pain in a population with low income and low health literacy. Patients in both treatments reported lower pain by the end of treatment, and the effects were maintained at one year. Patients in the CBT group also reported less depression. The current study uses a larger sample, and directly compares these psychosocial treatments to medical treatment-as-usual to seek better evidence for or against their widespread use in community settings. Our research questions: 1. In people with chronic pain and low income and/or low literacy, does participating in a health-literacy-adapted psychosocial treatment improve their pain and interference in daily activities due to pain by the end of treatment when compared with a group receiving typical medical care, and are these effects maintained 6 months later? 2. Does participation in the CBT pain management group improve symptoms of depression better than a pain education group by the end of treatment, and are these effects maintained 6 months later? In partnership with a federally qualified health center, we will enroll 294 patients with chronic pain. Main outcomes will be patient-reported pain intensity, pain interference, depression, and perceived change. From an earlier trial, we expect that our participants will be ~75% female and ~70% African American, and will have low literacy and low income (~60% in the low 15% nationally on word reading, and 90% at or below the poverty threshold).