Chronic Hepatitis C Clinical Trial
Official title:
Observational Study of B-Cell Non Hodgkin Lymphomas (NHL) in Patients With Hepatitis C Virus
An prospective / retrospective multicenter observational study whose objectives are to understand the interactions between hepatitis c virus and Non Hodgkin lymphomas. The characteristics , evolution and treatment of diseases will be observed from the study.
Main objectives are:
- Description of the clinical and histological characteristics, treatment and evolution
of these NHL.
- Study their physiopathology by immunological, virologic and molecular studies.
The study included prospective or retrospective patients with B- Cell Non-Hodgkin lymphomas
(NHL) associated with chronic hepatitis C. The patients are diagnosed or in remission of
lymphoma, in relapse or failure of treatments.
The enrolment period is 6 years and the total study lasts 8 years.
- "Prospective patients" are followed every 6 months during one year, and all the years
during 2 or 5 years.
- "Retropective patients" are followed all the years during 2 or 5 years. At each
follow-up, a blood sample of 50ml is withdrawn allowing ancillary studies.
The enrollment is estimated at 140 patients.
;
Observational Model: Case-Only
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