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Chronic Disease clinical trials

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NCT ID: NCT03086590 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

EVALUATION OF RESPIRATORY MECHANICS AND FUNCTIONALITY IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Start date: November 1, 2016
Phase:
Study type: Observational

To associate a lean mass, peripheral muscle strength, kinematic thoracic-abdominal, respiratory metabolic response, mobility and diaphragmatic thickness, verifying its relation with the obstruction level of COPD

NCT ID: NCT03075709 Enrolling by invitation - Clinical trials for Pulmonary Disease, Chronic Obstructive

The Development, Implementation and Evaluation of Clinical Pathways for Chronic Obstructive Pulmonary Disease (COPD) in Saskatchewan

Start date: September 30, 2017
Phase:
Study type: Observational

Chronic obstructive pulmonary disease (COPD) has substantial economic and human costs. To minimize these costs high quality guidelines have been developed. However, development of guidelines alone rarely results in changes to practice. One method of integrating guidelines into professional practice is the use of clinical pathways (CPWs). The investigators are working with local stakeholders to develop CPWs for COPD with the aims of improving quality of care and guideline adherence while reducing healthcare utilization. The CPWs will utilize several steps including: standardizing diagnostic training, implementing and unifying common components of chronic disease care, coordinating the provision of education and reconditioning programs, and ensuring disease specific care utilizes and delivers evidence-informed practices. In addition, the investigators have worked to identify evidence-informed strategies for the implementation of the CPWs. Efforts are underway to tailor these implementation strategies for the local context. The investigators will conduct a three-year quantitative health services research project using an interrupted time series (ITS) design in the form of a multiple baseline approach with control groups. The CPW will be implemented in two Saskatchewan health regions (experimental groups) and two health regions will act as controls (control groups). The experimental and control groups will each contain one urban and one rural health region. This project is expected to improve quality of life and reduce healthcare utilization. The project will also provide evidence on the effects of CPWs in both urban and rural settings. If the pathways are found effective the investigators will work with all stakeholders to implement similar CPWs for the remaining health regions in the province.

NCT ID: NCT03073564 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Effect of Expiratory Positive Pressure on Dynamic Hyperinflation and Ability to Exercise With Upper Limbs in COPD

Start date: December 1, 2015
Phase: N/A
Study type: Interventional

The study will evaluate the effect of positive airway expiratory pressure (EPAP) on patients with chronic obstructive pulmonary disease (COPD) during submaximal upper limb exercise.

NCT ID: NCT03067207 Completed - Chronic Illness Clinical Trials

In-Person vs e-Health Mindfulness-Based Intervention for Adolescents With Chronic Illness

Start date: November 4, 2016
Phase: N/A
Study type: Interventional

This study will seek to compare the effect of a mindfulness meditation program for adolescents with chronic illness delivered either in person or via an online platform. The 8-week program will combine meditation practices, breathing exercises and group discussions. Participants will be recruited from different general and specialized clinics at the Hospital for Sick Children and will be allocated to either an in-person or the online group through a random process (like tossing a coin). The study will aim to recruit 60 participants ages 13-18. Each participant will provide data through research questionnaires, recorded interviews and saliva samples.

NCT ID: NCT03063138 Completed - Diabetes Mellitus Clinical Trials

Evaluation of 3D Imaging Ulcer Camera

3D-DFU
Start date: August 1, 2015
Phase: N/A
Study type: Observational

The aim of the study is to evaluate the intra- and inter-rater variability of wound measurements using the 3D camera and to compare with standard measurement methods (2D image method and gel injection). Forty-eight patients with wounds of various sizes are measured by four clinicians. Each wound is measured twice with the 3D camera, once by 2D image method and once by gel injection into wound cavity by two clinicians.

NCT ID: NCT03062670 Completed - Chronic Disease Clinical Trials

Team-Based Delivery of Care in Outpatient Settings

Start date: January 31, 2017
Phase: N/A
Study type: Interventional

Through this research we intend to evaluate whether a team-based care delivery approach using daily huddles is effective in improving caregiver and patient outcomes in primary care setting. This approach is expected to not only lead to effective primary care delivery outcomes, but also result in greater team morale, reduced burnout, and a higher rate of innovation.

NCT ID: NCT03055988 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Cardiovascular Function in COPD Patients

Start date: March 29, 2017
Phase: Phase 4
Study type: Interventional

The objectives of the study are to explore the effect of treatment with tiotropium + olodaterol fixed dose combination (FDC) compared to fluticasone propionate + salmeterol FDC on: - reversal of left ventricular diastolic dysfunction assessed with cardiac magnetic resonance (CMR) imaging, - measures of arterial stiffness assessed by CMR and pulse wave analysis (PWA), - reduction of hyperinflation assessed with body plethysmography and - post dose spirometry.

NCT ID: NCT03052959 Completed - Clinical trials for Cancer and Chronic Disease Prevention

BETTER HEALTH: Durham

Start date: October 2, 2017
Phase: N/A
Study type: Interventional

The BETTER intervention consists of supportive meetings between a specially trained prevention practitioner nurse and individuals aged 40-64 years to review recommended chronic disease prevention and screening activities (CDPS). The prevention practitioner nurse will assist participants to identify goals for accomplishing CDPS activities in the next 6 months. Promotion, recruitment of participants and delivery of the BETTER intervention will be adapted to meet the needs of the residents through the use of participatory research methods and community engagement strategies. The study population consists of individuals aged 40-64 years living in 10 designated areas or "clusters" within Durham Region in Oshawa and Whitby. Objectives: 1. Help people in the designated areas identify personal goals related to chronic disease prevention and screening activities. 2. Evaluate whether the prevention practitioner was effective in helping people achieve their goals and explore whether this type of intervention could work in other settings. 3. Share what the investigators learn with government and other public health units in Ontario and across Canada. Some clusters will receive the BETTER intervention right away and other clusters will be in a wait-list control group to receive the intervention 6 months later. Our main outcome is the change in a score that considers the number of preventive health items a person has achieved during the 6 months. The investigators will also be doing in-depth interviews and focus groups with health care providers, community organizations and people who live in the designated areas to understand whether the primary practitioner was effective.

NCT ID: NCT03048565 Terminated - Chronic Illness Clinical Trials

A Trial of an Online Mindfulness Based Programme for Informal Caregivers of People With Chronic Illnesses

Start date: September 13, 2017
Phase: N/A
Study type: Interventional

This is a pilot feasibility study testing a mindfulness based intervention with caregivers of people with chronic illnesses

NCT ID: NCT03041571 Withdrawn - Cancer Clinical Trials

Impact of Early Implementation of Narrative Medicine Techniques on Patient Centered Attitudes of Medical Students

Start date: March 1, 2017
Phase:
Study type: Observational

A qualitative study assessing the impact of early narrative medicine practice on Medical Honors Program (MHP) students' attitudes regarding patient-centered interactions, through interviewing patients with chronic or life-limiting illnesses to obtain their illness stories. MHP students will develop a patient narrative for the patients interviewed. These narratives will be edited by the patient, and, with the permission of the patients, may be published as a collection of stories.