Cerebral Vasospasm Clinical Trial
Official title:
A Safety and Feasibility Study of the Use of Cervical Spinal Cord Stimulation for Treatment of Cerebral Vasospasm in Patients With Aneurysmal Subarachnoid Hemorrhage
The study is a non-blinded evaluation of the use of cervical spinal cord stimulation (SCS) for treatment of patients with Hunt and Hess grade 1-2 subarachnoid hemorrhage and evidence of cerebral vasospasm.
The study is a non-blinded evaluation of the use of cervical spinal cord stimulation (SCS) for treatment of patients with Hunt and Hess grade 1-2 subarachnoid hemorrhage and evidence of cerebral vasospasm. Stimulation will be provided with electrodes placed percutaneously in the upper cervical epidural space. The outcome of 5 patients will be studied with focus on possible adverse events related to the intervention. Vasospasm response to treatment will be measured as a secondary outcome. Middle cerebral artery flow velocity will be followed by transcranial Doppler and clinical outcome measured by NIH stroke scale. Flow velocities will be monitored daily by transcranial Doppler and NIH stroke scale performed daily for 7 days, after which spinal cord stimulation will be discontinued and the epidural lead removed. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02275949 -
Acupuncture for Cerebral Vasospasm After Subarachnoid Hemorrhage
|
N/A | |
| Completed |
NCT02389634 -
Identification of Novel Molecular Markers for Vasospasm
|
||
| Completed |
NCT00962546 -
Computed Tomographic (CT) Perfusion and CT Angiography as Screening Tools for Vasospasm Following Subarachnoid Hemorrhage
|
N/A | |
| Not yet recruiting |
NCT04512859 -
Stellate Ganglion Block in Preventing Cerebral Vasospasm Secondary to Subarachnoid Hemorrhage
|
N/A | |
| Completed |
NCT01024972 -
Safety Study of Dantrolene in Subarachnoid Hemorrhage
|
Phase 1/Phase 2 | |
| Completed |
NCT00692744 -
Quality of Life in Elderly After Aneurysmal Subarachnoid Hemorrhage (SAH)
|
N/A | |
| Completed |
NCT04208477 -
"The Effect of Stellate Ganglion Block in Severe Brain Injury"
|
N/A | |
| Recruiting |
NCT06303349 -
Predictive Model for the Occurrence of Cerebral Vasospasm Complicating Subarachnoid Haemorrhage by Combined Analysis of the Kinetics of a Panel of Biomarkers.
|
N/A | |
| Recruiting |
NCT02129413 -
Safety Study of Carotid Body Neurostimulation to Treat Cerebral Vasospasm
|
N/A | |
| Terminated |
NCT00582868 -
Use of Brain Oxygen Tension Level and Cleaved-tau Protein to Detect Vasospasm After SAH
|
N/A | |
| Terminated |
NCT00487461 -
Use of Simvastatin for the Prevention of Vasospasm in Aneurysmal Subarachnoid Hemorrhage
|
N/A | |
| Withdrawn |
NCT01878136 -
Effect of Intraventricular tPA Following Aneurysmal Subarachnoid Hemorrhage
|
Phase 1/Phase 2 | |
| Withdrawn |
NCT01091870 -
Sildenafil for Prevention of Cerebral Vasospasm
|
Phase 2 | |
| Completed |
NCT03214705 -
Role of CT Perfusion in Predicting Poor Outcome After Subarachnoid Hemorrhage
|
||
| Recruiting |
NCT05150002 -
Cervical Spinal Cord Stimulation in Patients With Cerebral Vasospasm After Subarachnoid Haemorrhage: VasoStim Study
|
N/A | |
| Completed |
NCT01187420 -
Bilateral Bispectral Index (BIS) Study
|
N/A | |
| Enrolling by invitation |
NCT05230134 -
Cervical Sympathetic Block in Patients With Cerebral Vasospasm
|
N/A | |
| Withdrawn |
NCT00871065 -
Safety Study of Sildenafil in Treatment of Cerebral Aneurysm Vasospasm
|
Phase 2 | |
| Recruiting |
NCT04691271 -
Stellate Ganglion Block and Cerebral Vasospasm
|
N/A | |
| Recruiting |
NCT02432157 -
Safety and Feasibility of Hypertonic Saline Solution After Aneurysmal Subarachnoid Hemorrhage:
|
Phase 1/Phase 2 |