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Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT06199869
Other study ID # CVA2024.SMuRFless1
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date January 22, 2024
Est. completion date January 31, 2025

Study information

Verified date January 2024
Source Jordan Collaborating Cardiology Group
Contact Ayman Hammoudeh, MD, FACC
Phone +96265001000
Email hammoudeh_ayman@yahoo.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

A growing number of patients develop atherosclerotic cardiovascular disease (ASCVD) despite the absence of standard modifiable risk factors (SMuRF-less). There is scarcity of studies that address this issue in the Middle Eastern population.


Description:

Atherosclerotic coronary artery disease (ASCAD) claims millions of lives annually on a global level and is the leading cause of death in the Middle East. There are four standard modifiable cardiovascular risk factors (SMuRFs): hypertension, type 2 diabetes mellitus, dyslipidemia, and smoking. These are very common in the Middle East and are crucial to be screened for and addressed in an affective manner. However, an increasing proportion of patients with ASCVD have none of these individual factors (SMuRF-less). Globally, this proportion comprises 11.6% of individuals with stable coronary disease and heart attack. No prior study has addressed the issue of the prevalence of SMuRF-less patients among the whole population of individuals with ASCVD in the Middle East.


Recruitment information / eligibility

Status Recruiting
Enrollment 5000
Est. completion date January 31, 2025
Est. primary completion date January 1, 2025
Accepts healthy volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - A diagnosis of atherosclerotic cardiovascular disease (ASCVD). - Ability to fill the clinical form that evaluates the presence or absence of cardiovascular risk factors including the 4 SMuRFs. Exclusion Criteria: - Atherosclerotic cardiovascular disease diagnosed before the age of 18 years. - Inability to give detailed history of prespecified risk factors.

Study Design


Intervention

Other:
Evaluation of risk factors by direct interview with subjects who have atherosclerotic cardiovascular patients
Individuals identified with a diagnosis of ASCVD will fill a one page form of the associated risk factors they have

Locations

Country Name City State
Jordan Istishari Hospital Amman
Jordan Yarmouk University School of Medicine Irbid

Sponsors (3)

Lead Sponsor Collaborator
Jordan Collaborating Cardiology Group The Jordan Cardiovascular Research Group JoCVRG, Yarmouk University School of Medicine

Country where clinical trial is conducted

Jordan, 

Outcome

Type Measure Description Time frame Safety issue
Primary Prevalence of patients who do not any of the four SMuRFs Group of patients with definite ASCVD who do not have hypertension, diabetes, dyslipidemia or smoking. Up to 4 weeks after study enrollment
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