Cardiovascular Diseases Clinical Trial
Official title:
An International Multicentre Randomized Controlled Trial of Intensive Insulin Therapy Targeting Normoglycemia In Acute Myocardial Infarction: the RECREATE (REsearching Coronary REduction by Appropriately Targeting Euglycemia) Pilot Study
Insulin will safely reduce glucose levels in patients with acute ST-elevation myocardial infarction and admission hyperglycemia.
Patients will be randomly assigned to either the control arm and will receive usual AMI care
or the experimental arm, which will include routine AMI care as well as intensive therapy
intervention.
In addition to the capillary blood glucose measurements obtained to titrate insulin doses in
the experimental arm patients, laboratory plasma glucose will be drawn in all patients at
randomization, 10, 24, 48, and 72 hours post randomization, 7 days post randomization (or
hospital discharge if that occurs first), and 30 days post randomization.
;
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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