Cardiovascular Diseases Clinical Trial
To conduct a baseline survey on cardiovascular, respiratory, and other major systemic disease and risk factors in members of the Vietnam Era Twin Registry.
BACKGROUND:
The Vietnam Veteran Twin Registry, maintained by the NAS-NRC, was created with funding from
the Veterans Administration. Department of Defense records were searched for subjects born
between 1939-1957 and having the same last name and date of birth. Follow-up of induction
records determined if the subjects were twins.
The registry supplemented the older World War II Veterans Twin Registry supported by the
National Heart, Lung, and Blood Institute. The new registry provided an opportunity to
create a resource with Black and Hispanic twins as well as whites. The new registry also
included data on greater educational, socioeconomic, and lifestyle diversity than was
available in the World War II Veterans Twin Registry.
DESIGN NARRATIVE:
During the first year a mailed questionnaire was designed which provided baseline data on
family history, body size, morbidity, psychosocial characteristics, smoking, alcohol
consumption, diet, physical activity, and drug use. The baseline data were used for analysis
of cardiovascular, pulmonary, and blood diseases, and for follow-up. From the original
survey, the Veterans Administration provided magnetic tape data on zygosity, smoking,
alcohol consumption, heart, lung, and blood diseases, discharge rank, education, occupation,
and family income. The questionnaire was completed by almost 8,900 individuals including
over 3,000 twin pairs.
The study completion date listed in this record was obtained from the "Completed Date"
entered in the Query View Report System (QVR).
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