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Cardiovascular Diseases clinical trials

View clinical trials related to Cardiovascular Diseases.

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NCT ID: NCT00000609 Completed - Heart Failure Clinical Trials

Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT)

Start date: May 1997
Phase: Phase 3
Study type: Interventional

To compare conventional treatment of congestive heart failure (CHF) with two experimental interventions: amiodarone and an implantable cardioverter-defibrillator (ICD).

NCT ID: NCT00000608 Completed - Hypertension Clinical Trials

Dietary Patterns, Sodium Intake and Blood Pressure (DASH - Sodium)

Start date: February 1997
Phase: Phase 2
Study type: Interventional

To compare the effects of three levels of dietary sodium and two patterns of diet (a control diet and an intervention diet high in fruits, vegetables, and low fat dairy products and low in fat) on blood pressure in individuals with higher than optimal blood pressure or with Stage 1 hypertension.. DASH - Sodium built on and extended the results of the NHLBI-initiated Dietary Approaches to Stop Hypertension (DASH) study.

NCT ID: NCT00000607 Completed - Heart Failure Clinical Trials

Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure (REMATCH)

Start date: October 1997
Phase: Phase 3
Study type: Interventional

To conduct a randomized, unblinded clinical trial comparing the left ventricular assist device (LVAD) with maximum medical management in patients with end-stage heart failure who were not candidates for heart transplantation.

NCT ID: NCT00000605 Completed - Clinical trials for Cardiovascular Diseases

Estrogen and Graft Atherosclerosis Research Trial (EAGER)

Start date: August 1996
Phase: Phase 3
Study type: Interventional

To determine if postmenopausal hormone replacement therapy in women following coronary bypass surgery would reduce the occurrence of graft occlusion and delay the development of graft atherosclerosis.

NCT ID: NCT00000604 Completed - Clinical trials for Cardiovascular Diseases

Influence of CPB Temperature on CABG Morbidity

Start date: January 1994
Phase: Phase 2
Study type: Interventional

To compare three accepted modes of myocardial preservation, warm, tepid, and cold blood cardioplegia, coinciding with normothermic (37 degrees centigrade), tepid (32 degrees centigrade) and hypothermic (8 to 10 degrees centigrade) cardiopulmonary bypass (CPB) to define differences in neurologic function in coronary artery bypass graft (CABG) patients.

NCT ID: NCT00000601 Completed - Clinical trials for Cardiovascular Diseases

Postmenopausal Hormone Therapy in Unstable Angina

Start date: July 1995
Phase: Phase 3
Study type: Interventional

To determine if estrogen therapy in postmenopausal women with unstable angina reduces the incidence of ischemic episodes.

NCT ID: NCT00000600 Terminated - Clinical trials for Cardiovascular Diseases

Vitamin E and C to Slow Progression of Common Carotid Artery Plaque Build-Up

Start date: June 1995
Phase: Phase 2
Study type: Interventional

This study will evaluate the effects of vitamin E supplementation in retarding the progression of common carotid artery intima-media thickening in African Americans.

NCT ID: NCT00000599 Completed - Clinical trials for Cardiovascular Diseases

Cholesterol-Lowering Atherosclerosis Study (CLAS)

Start date: June 1980
Phase: Phase 3
Study type: Interventional

To determine whether combined therapy with the lipid lowering agents colestipol hydrochloride plus niacin would produce significant change in coronary, carotid, and femoral artery atherosclerosis and coronary bypass graft lesions as determined by angiography. Also, to determine possible correlations between lesion changes and plasma lipid and lipoprotein cholesterol levels and to explore interrelationships of atherosclerosis change in femoral, coronary, and carotid arteries.

NCT ID: NCT00000598 Completed - Clinical trials for Cardiovascular Diseases

Diet and Exercise for Elevated Risk (DEER)

Start date: August 1991
Phase: Phase 3
Study type: Interventional

To determine the effect in men and postmenopausal women with elevated LDL-cholesterol and low HDL-cholesterol of an exercise regimen with or without the National Cholesterol Education Program (NCEP) Step Two diet compared to usual care control group on HDL- and LDL-cholesterol.

NCT ID: NCT00000594 Completed - Clinical trials for Cardiovascular Diseases

NHLBI Type II Coronary Intervention Study

Start date: November 1971
Phase: Phase 3
Study type: Interventional

To determine whether lowering of cholesterol with cholestyramine in a population with Type II hyperlipidemia led to a decreased rate of progression (a regression of coronary artery disease) as demonstrated by death, myocardial infarction, or progression of disease on angiography.