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Carcinoma clinical trials

View clinical trials related to Carcinoma.

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NCT ID: NCT02941861 Completed - Liver Cancer Clinical Trials

Factors Influencing the 3-Year Recurrence of Liver Carcinoma After Surgery

Start date: August 2016
Phase: N/A
Study type: Observational

Objective: 1. To study the factors that influence the 3- year recurrence of liver carcinoma after surgery 2. To study the related factors affecting recurrence of liver carcinoma after surgery

NCT ID: NCT02940925 Completed - Clinical trials for Nasopharyngeal Carcinoma

TPC vs PF as Induction Chemotherapy Combined With CCRT for Stage IVa-b Nasopharyngeal Carcinoma

Start date: October 20, 2016
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the survival and toxicity of TPC (TAXOL, DDP AND CAPECITABINE ) VS PF (cisplatin and 5-Fluorouracil) as induction chemotherapy combined with concurrent chemoradiotherapy (CCRT) for stage IVa-b nasopharyngeal carcinoma patients in endemic area.

NCT ID: NCT02940496 Completed - Clinical trials for Hepatitis C Infection

Pembrolizumab With or Without Elbasvir/Grazoprevir and Ribavirin in Treating Patients With Advanced Refractory Liver Cancer

Start date: December 9, 2016
Phase: Phase 2
Study type: Interventional

This phase I/II clinical trial studies the side effects of pembrolizumab with or without elbasvir/grazoprevir and ribavirin and to see how well they work in treating patients with liver cancer that has spread to other places in the body and does not respond to previous treatment. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Elbasvir/grazoprevir and ribavirin may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving pembrolizumab in combination with elbasvir/grazoprevir and ribavirin may work better in treating patients with liver cancer than with pembrolizumab alone.

NCT ID: NCT02939300 Completed - Clinical trials for Leptomeningeal Carcinomatosis

Ipilimumab and Nivolumab in Leptomeningeal Metastases

Start date: February 15, 2018
Phase: Phase 2
Study type: Interventional

This research study is studying a combination of two drugs as a possible treatment for Leptomeningeal Metastases. The names of the study interventions involved in this study are: - Ipilimumab - Nivolumab

NCT ID: NCT02939027 Completed - Clinical trials for Carcinoma, Basal Cell

Study of Electronic Brachytherapy for Cutaneous Basal Cell Carcinoma

Start date: July 2013
Phase: N/A
Study type: Interventional

Electronic brachytherapy (EBT) offers an isotope-free radiation therapy modality for the treatment of specific skin lesions, especially non-melanoma skin cancers (NMSC). Within the treatment of NMSC, surgical removal of the lesion is currently the treatment of choice for the majority of cases. However in an estimated 10-15% of NMSC patients, surgery might not be the best treatment option. Location of the tumour in cosmetically sensitive areas, patient comorbidities, old age, use of anti-coagulation etc. might all be reasons to select radiotherapy as first choice of treatment. The objective of ths study will be to determine histologically confirmed clinical efficacy, safety, and usability of Electronic Brachytherapy, an innovative treatment for Basal Cell Carcinoma (BCC).

NCT ID: NCT02938273 Completed - Clinical trials for Carcinoma, Squamous Cell of Head and Neck

Bioimmunoradiotherapy (Cetuximab/RT/Avelumab)

Start date: February 1, 2017
Phase: Phase 1
Study type: Interventional

This is an open-label phase IB trial with Bioimmunoradiotherapy, i.e. concurrent radiotherapy with intravenous administration of cetuximab and avelumab followed by avelumab maintenance therapy in patients with locally advanced head and neck cancer, unfit for cisplatin.

NCT ID: NCT02937818 Completed - Clinical trials for Platinum Refractory Extensive-Stage Small Cell Lung Carcinoma

A Phase II, Study to Determine the Preliminary Efficacy of Novel Combinations of Treatment in Patients With Platinum Refractory Extensive-Stage Small-Cell Lung Cancer

Start date: November 28, 2016
Phase: Phase 2
Study type: Interventional

Study design This is a Phase II, open-label, multi-drug, multi-center, multi-arm, signal-searching study in patients with extensive-stage small-cell lung cancer (SCLC) who have refractory or resistant disease from prior platinum-based chemotherapy.

NCT ID: NCT02936323 Completed - Clinical trials for Neuroendocrine Tumors

PEN-221 in Somatostatin Receptor 2 Expressing Advanced Cancers Including Neuroendocrine and Small Cell Lung Cancers

Start date: December 8, 2016
Phase: Phase 1/Phase 2
Study type: Interventional

Protocol PEN-221-001 is an open-label, multicenter Phase 1/2a study evaluating PEN-221 in patients with SSTR2 expressing advanced gastroenteropancreatic (GEP) or lung or thymus or other neuroendocrine tumors or small cell lung cancer or large cell neuroendocrine carcinoma of the lung.

NCT ID: NCT02927626 Completed - Clinical trials for Hepatocellular Carcinoma

Yang Yin Fu Zheng Therapy in HBV Associated Hepatocellular Carcinoma

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Start date: August 2016
Phase: Early Phase 1
Study type: Interventional

Clinical research of Yang Yin Fu Zheng therapy in HBV associated hepatocellular carcinoma basing on immune microenviroment.The purpose of this study is to observe the efficacy of routine medical care combined with Yang Yin Fu Zheng therapy for patients belong to HBV-HCC.

NCT ID: NCT02921269 Completed - Clinical trials for Cervical Adenocarcinoma

Atezolizumab and Bevacizumab in Treating Patients With Recurrent, Persistent, or Metastatic Cervical Cancer

Start date: March 10, 2017
Phase: Phase 2
Study type: Interventional

This phase II trial studies how well atezolizumab and bevacizumab work in treating patients with cervical cancer that has come back, remains despite treatment, or has spread to other places in the body. Monoclonal antibodies, such as atezolizumab and bevacizumab, may shrink tumor cell and interfere with the ability of tumor cells to grow and spread.