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Carcinoma, Hepatocellular clinical trials

View clinical trials related to Carcinoma, Hepatocellular.

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NCT ID: NCT02774161 Completed - Cirrhosis Clinical Trials

B-mode Ultrasound Imaging in Detecting Early Liver Cancer

Start date: May 2016
Phase: N/A
Study type: Interventional

This pilot trial studies how well B-mode ultrasound imaging works in detecting liver cancer that is early in its growth and may not have spread to other parts of the body. Diagnostic procedures, such as B-mode ultrasound imaging, may help find and diagnose liver cancer and find out how far the disease has spread.

NCT ID: NCT02764801 Completed - Clinical trials for Hepatocellular Carcinoma

Contrast-enhanced Ultrasound Evaluation of Chemoembolization

Start date: April 2016
Phase: Phase 3
Study type: Interventional

The primary objective of this trial is to evaluate the sensitivity and specificity of 2D and 4D contrast enhanced ultrasound for monitoring transarterial chemoembolization (TACE) response 1-2 weeks and 1 month post treatment as an alternative to contrast-enhanced magnetic resonance (MRI) or computed tomography (CT) imaging

NCT ID: NCT02762721 Completed - Cholangiocarcinoma Clinical Trials

Analysis of Oncogenes in Intrahepatic Cholangiocarcinoma or Mixed Hepatocellular-Cholangiocarcinoma in Tumor Tissue Samples

Start date: June 6, 2016
Phase: N/A
Study type: Observational

The primary objective of this study is to estimate the frequency of FGFR2 fusions in archived intrahepatic cholangiocarcinoma (iCCA) or mixed hepatocellular-cholangiocarcinoma (HCC-CCA) tumor samples

NCT ID: NCT02745483 Completed - Clinical trials for Hepatocellular Carcinoma

Radiofrequency Ablation Using Octopus Electrodes for Treatment of Focal Liver Malignancies: Follow-up Study

Start date: November 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study is to compare the therapeutic outcomes and safety of the study patients who received radiofrequency ablation (RFA) using separable clustered electrodes with those of a matched historical control group who had received RFA using multiple internally-cooled electrodes.

NCT ID: NCT02730611 Completed - Clinical trials for Hepatocellular Carcinoma

Metabolic Syndrome, Bile Acids, Hepatocellular Carcinoma and Cholangiocarcinoma

METSLIVER
Start date: March 2016
Phase:
Study type: Observational

Increasing rates of highly malignant hepatocellular carcinoma (HCC) and biliary tract cancers (GBTC) observed in Western populations may be related to obesogenic lifestyle factors and their metabolic consequences, such as metabolic syndrome (MetS), inflammation and altered production of bile acids (BA). Such lifestyle behaviours may induce changes in the gut microflora which in turn affect BA profiles, increasing their carcinogenicity. Some elevated BA may be oncogenic in exposed liver, bile ducts and gall bladder. Vertical sleeve gastrectomy may change bile acid composition. The aims of this study are: 1. whether specific presurgical bila acid profiles are predictive of efficacy of vertical sleeve gastrectomy, reflective of liver function and metabolic dysfunction; 2. whether specific presurgical bile acid profiles are predictive of the efficacy of sleeve gastrectomy

NCT ID: NCT02728219 Completed - Clinical trials for Recurrent Hepatocellular Carcinoma

Comparison of Treatment of Recurrent HCC With Repeat Hepatectomy,and TACE With AFP Conversion

HCCTACEAFP
Start date: May 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the treatment of recurrent hepatocellular carcinoma with repeat hepatectomy,and transcatheter arterial chemoembolization (TACE) with AFP conversion.

NCT ID: NCT02728193 Completed - Clinical trials for Hepatocellular Carcinoma

Standard Treatments of Very-early Stage Hepatocellular Carcinoma

Start date: December 2012
Phase: N/A
Study type: Interventional

The aim of our study was to elucidate the difference in the rates of complication, hospitalization days, medical expenses, MRI showed that the degree of tumor necrosis, and overall survival rates of the therapies between PEI, MVA and RFA, and make the standard for minimally invasive treatment of very early stage HCC.

NCT ID: NCT02727673 Completed - Clinical trials for Hepatocellular Carcinoma

Relationship Between Circulating Tumor Stem Cells and the Clinical Pathology

Start date: December 2012
Phase: N/A
Study type: Observational

The aim of this study is to establish a platform of detecting and sorting circulating tumor stem cells from peripheral blood in HCC patients; to investigate the relationship between circulating tumor stem cells and their effects on postoperative recurrence and metastasis, in order to provide a new therapeutic target for hepatocellular carcinoma treatment.

NCT ID: NCT02716766 Completed - Clinical trials for Carcinoma, Hepatocellular

Study of SECOX Versus Sorafenib as First-Line Treatment in Patients With Advanced Hepatocellular Carcinoma (HCC)

Start date: March 2016
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if sorafenib, capecitabine and oxaliplatin (SECOX) regimen is more effective than sorafenib alone in the treatment of advanced liver cancer.

NCT ID: NCT02705118 Completed - Clinical trials for Hepatocellular Carcinoma

Evaluation of Performance of Automatic Fusion for Radiofrequency Ablation of Hepatocellular Carcinoma

FAME-US
Start date: December 2015
Phase: N/A
Study type: Interventional

Fusion imaging of US and MRI is very helpful for interventional procedure such as radiofrequency ablation in liver. However, manual registration of US and magnetic resonance (MR) imaging is somewhat time-consuming and difficult for less-experienced physicians. Recently, automatic registration function was developed to help the fusion of US and CT/MRI imaging. The purpose of this trial is to compare the registration time and accuracy of manual registration system and automatic registration system.