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NCT ID: NCT03182010 Not yet recruiting - Clinical trials for Cesarean Section Scar

Ultrasound Evaluation of Cesarean Scar After Uterotomy Closure With Barbed and Conventional Sutures

Start date: August 2017
Phase: N/A
Study type: Interventional

The aim of this randomized control trial is to compare the residual myometrial thickness and the depth of cesarean section scar defect after uterine incision closure with barbed or conventional sutures.

NCT ID: NCT03183297 Not yet recruiting - Veisalgia Clinical Trials

Study to Evaluate the Pharmacokinetics and Pharmacodynamics of JMI-001

Start date: August 2017
Phase: Phase 1
Study type: Interventional

This will be a double-blind, placebo-controlled study with a 4-way crossover design with subjects administered study drug (JMI-001), placebo, fexofenadine alone and naproxen alone on different study days, in conjunction with a quantity of alcohol estimated to be sufficient to produce a hangover the next day. The primary objective of the study is the evaluate the pharmacokinetics (PK) and pharmacodynamics (PD) of two different doses of JMI-001 administered in conjunction with alcohol to healthy adult subjects.

NCT ID: NCT03183362 Not yet recruiting - Cesarean Section Clinical Trials

Comparison of Barbed and Conventional Sutures in Adhesion Formation Following Cesarean Section

Start date: August 2017
Phase: N/A
Study type: Interventional

The aim of this randomized controlled trial is to determine whether the use of barbed sutures to close uterine incision at cesarean section is associated with more postoperative adhesions compared with conventional sutures or not.

NCT ID: NCT03191305 Not yet recruiting - Clinical trials for Cerebral Venous Thrombosis

Comparison of the Efficacy of Rivroxaban to Coumadin( Warfarin ) in Cerebral Venous Thrombosis

CVT
Start date: August 2017
Phase: N/A
Study type: Interventional

In past few years new anticoagulants have been developed which directly inhibit thrombin or factor X.factor x inhibitor is available in Pakistan. The superior efficacy of Rivroxaban has been shown in Deep Venous Thrombosis in EINSTEIN study (3).Its definite superiority in prevention of embolic stroke in nonvalvular atrial fibrillation is evidenced by the study ROCKET AF (4). With Rivroxaban no monitoring is required, and also there are no drug interactions .There are few pilot studies of using Rivroxaban in cerebral venous thrombosis. This study is therefore required to find its efficacy in CVT patients as well as its comparison with Coumadin

NCT ID: NCT03195582 Not yet recruiting - Bone Loss Clinical Trials

The Effect of Chlorohexidine Gel on Tissue Healing Following Surgical Exposure of Dental Implants

Start date: August 2017
Phase: Phase 1/Phase 2
Study type: Interventional

The aim of this study is to evaluate the healing of peri-implat tissue following surgical uncovering with the adjunctive use of Chlorohexidine (CHX) gel.

NCT ID: NCT03196674 Not yet recruiting - Fracture Humerus Clinical Trials

The Effect of Controlled Feedback on the Rehabilitation of Individuals With Disability Due to Stiff Shoulder Following Trauma

Start date: August 2017
Phase: N/A
Study type: Interventional

This study will compare the effect of manipulated vs. non-manipulated feedback during the rehabilitation of individuals with disability due to stiff shoulder following multiple trauma. This will be accomplished using the state-of-the-art real-time motion capture technology.

NCT ID: NCT03205930 Not yet recruiting - NSCLC Stage IV Clinical Trials

Neo-MASCT Immunotherapy for Advanced NSCLC.

Start date: August 2017
Phase: Phase 1/Phase 2
Study type: Interventional

Neoantigen (Neo)is a new targets for immune cells,that the DC neoantigen immunotherapy was more effective in triggering specific T-cell responses. Neo-MASCT using the DC vaccine and neoantigen T cells .Dendritic cells(DC) was induced from autologous peripheral blood,and be loaded with antigens and re-infused. In vitro, antigen-pulsed DC can stimulate autologous T-cell proliferation and induction of autologous specific cytotoxic T-cells(CTL),similarly re-infused. The study is aimed to evaluate the safety of Neo-MASCT in patients with advanced NSCLC.

NCT ID: NCT03206684 Not yet recruiting - Cervical Cancer Clinical Trials

To Evaluate the Efficacy and Safety of PEG-rhG-CSF(Jinyouli®) in Reducing Neutropenia in Patients With Cervical Cancer

Start date: August 2017
Phase: Phase 4
Study type: Interventional

A Prospective, open, randomized, controlled clinical study to evaluate the efficacy and safety of PEG-rhG-CSF(PEGylated recombinant human granulocyte stimulating factor injection) in reducing neutropenia during TP(docetaxel+cisplatin) regiment simultaneous radiochemotherapy and adjuvant chemotherapy in patients with cervical cancer

NCT ID: NCT03211572 Not yet recruiting - Breast Cancer Clinical Trials

The EMPOwER Study Evaluating Multiparameter Gene Testing as a Predictor of Short Term Endocrine Therapy Response in Hormone Receptor Positive Breast Cancers

OTT 17-01
Start date: August 2017
Phase: Phase 2
Study type: Interventional

Evaluating Multiparameter Gene Testing as a Predictor of Short Term Endocrine Therapy Response in Hormone Receptor Positive Breast Cancers

NCT ID: NCT03212612 Not yet recruiting - Endometriosis Clinical Trials

Galectin-3 in Patients With Endometriosis

Start date: August 2017
Phase: N/A
Study type: Observational

The exact cause of endometriosis is unknown ,so our study is to investigate the relationship between Galectin-3 and endometriosis by comparing between its level in healthy and endometriosis women. Also, we will measure the level of oxidative stress markers in endometrium of both healthy and endometriosis women and investigate the correlaton between them and galectin-in endometriosis women.