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NCT ID: NCT02925806 Enrolling by invitation - Drug Abuse Clinical Trials

Evaluation of Drug Utilization Patterns for Extended Release/Long Acting Opioids and Comparator Products

Start date: n/a
Phase: N/A
Study type: Observational

A drug utilization study will be performed to describe trends in the number of prescriptions and patients for class REMS ER/LA opioids and comparator products.

NCT ID: NCT02075684 Enrolling by invitation - Clinical trials for Renal Cortical Neoplasms

Office-based Percutaneous Ultrasound-guided Renal Biopsy

Start date: April 1, 2013
Phase: N/A
Study type: Interventional

The purpose of this research study is to create a prospectively maintained, multicenter database of patients undergoing renal biopsy for renal masses performed percutaneously (through skin), via an 18 gauge biopsy needle (.048 inches). In this database, the investigators will collect and maintain the data from the biopsy procedure. This will allow us to evaluate our experience with this procedure as well as to participate in multi-institutional collaborative studies in the future. At University of California Irvine, the investigators routinely biopsy patients with renal masses under real-time ultrasound control. Percutaneous renal biopsy under ultrasound guidance is a routine procedure performed to diagnose renal mass histopathology. The safety and efficacy of this procedure has been well documented in the literature. The indications for percutaneous renal biopsy have expanded as there has been a substantial increase in the number of renal masses that are being diagnosed, and the acceptance of percutaneous biopsy continues to expand in parallel. The biopsy procedure is part of your normal standard of care and if not being done for this research project.

NCT ID: NCT03165331 Enrolling by invitation - Burns Clinical Trials

Online Psychosocial Support for Young People With a Visible Difference: A Randomised Control Study

UNGFaceIT
Start date: April 1, 2016
Phase: N/A
Study type: Interventional

A visible difference can have a profound impact in a society with a massive emphasis on appearance and "looks". A vulnerable group is adolescents with a condition affecting their appearance as a result of injuries (burns, accidents), treatment (cancer), skin conditions or congenital anomalies (birthmarks, craniofacial conditions). Research has identified potential psychological difficulties, which, if not addressed, can lead to anxiety, depression, and eating disorders. In addition to medical treatment options, aiming at diminishing a difference that may be visible to others, young people with appearance concerns also need self-management skills. However, evidence-based interventions are scarce and specialised psychological treatment is difficult to reach. The Centre for Appearance Research (Bristol, UK) has developed an online intervention for adolescents, now translated into Norwegian (www.ungfaceit.no). UNG Face IT provides easy access to specialist advice and support via a home computer, using information, videos, and interactive activities. It provides advice, teaches coping and social skills, strengthening psychological adjustment to a visible difference. A systematic evaluation of the Norwegian version is needed. UNG Face IT could potentially address unmet needs, provide a cost-effective tool to reduce the need for "face-to-face" psychological and surgical/medical services, and contribute to make online health care available for young people with a visible difference.

NCT ID: NCT03234894 Enrolling by invitation - Bleeding Clinical Trials

Clinical Trial of the WC360 SiteSeal Adjunctive Compression Device Following Interventional Endovascular Procedures

SiteSeal
Start date: April 1, 2016
Phase: N/A
Study type: Interventional

This Clinical Study is a pivotal study to evaluate the safety of the SiteSealâ„¢ Adjunctive Compression Device across a broad array of patients undergoing interventional endovascular procedures.

NCT ID: NCT02721797 Enrolling by invitation - Clinical trials for Ehlers-Danlos Syndrome

Origins and Impact of EDS in Connective Tissues and Skin

Start date: April 1, 2017
Phase:
Study type: Observational

Ehlers-Danlos Syndrome (EDS) is an inherited disease of collagen, found in connective tissues, such as skin. EDS patients suffer from joint and skin problems (skin hyperextensibility, joint hypermobility) along with a large range of other disorders, including, delayed wound healing with atrophic scarring, easy bruising, tissue fragility, gastrointestinal and gum problems. There are many different types of EDS, with different mechanisms of action, and not all of these are well understood. This study will used advanced microscopy techniques called atomic force microscopy (AFM) and scanning electron microscopy (SEM) to analyse the changes in collagen as a result of EDS, compared to normal collagen. These changes will be viewed at the micron and nanoscale level (between 1,000 to 100,000 x magnification), and will focus on the differences in collagen construction through a process called cross-linking. These changes could potentially help clinicians understand the root cause of EDS symptoms, and provide a deeper knowledge of cross-linking disorders in collagen. Increasing our knowledge of how collagen is affected in EDS patients, may lead to improved treatment options for patients.

NCT ID: NCT03096665 Enrolling by invitation - Clinical trials for Cardiovascular Diseases

Effectiveness of Point of Care Blood Analysis Obtained From Skin Puncture Blood

Start date: April 1, 2017
Phase: N/A
Study type: Observational

This study aimed to evaluate the correlation between the point of care blood analysis obtained from skin puncture blood and conventional blood analysis obtained from venous and arterial blood.

NCT ID: NCT03107975 Enrolling by invitation - Clinical trials for Spastic Cerebral Palsy

Effect of Human Amniotic Epithelial Cells on Children With Spastic Cerebral Palsy

Start date: April 1, 2017
Phase: Phase 1
Study type: Interventional

This study aimed to evaluate the therapeutic potential of human amniotic epithelial cell (hAEC) transplant in the management of children with spastic cerebral palsy.

NCT ID: NCT03115892 Enrolling by invitation - Halitosis Clinical Trials

Green Tea With Aloe Vera Mouthwash and Chlorohexidine Mouthwash

RCT
Start date: April 1, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

The Effect of Mouthwash Containing Green Tea With Aloe Vera and Chlorhexidine Mouthwash on Oral Malodour Among a Group of Egyptian Children: Randomized Clinical Trial

NCT ID: NCT03040778 Enrolling by invitation - Avascular Necrosis Clinical Trials

Pentoxifylline and Tocopherol (PENTO) in the Treatment of Medication-related Osteonecrosis of the Jaw (MRONJ)

Start date: April 1, 2018
Phase: Phase 3
Study type: Interventional

The overall purpose of this project is to answer the following clinical question: Among Medication-Related Osteonecrosis of the Jaw (MRONJ) patients, do those who are treated with the Pentoxifylline and Tocopherol (PENTO) regimen and standard of care, when compared to those treated with standard of care alone, have decreased areas of exposed bone after one year of treatment?

NCT ID: NCT03396276 Enrolling by invitation - Opioid Use Disorder Clinical Trials

Houston Emergency Opioid Engagement System

HEROES
Start date: April 1, 2018
Phase: Phase 4
Study type: Interventional

The Houston Emergency Response Opioid Engagement System (HEROES) is a community-based research program integrating assertive outreach, medication-assisted treatment, behavioral counseling, peer recovery support, and paramedic follow-up in Houston Texas. The objective is to compare differences in engagement and retention in treatment for individuals with opioid use disorder.