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NCT ID: NCT00493662 Completed - Dry Eye Clinical Trials

Cross-Over Evaluation of Two Lubricating Eye Drops

Start date: n/a
Phase: Phase 4
Study type: Interventional

To evaluate the efficacy of two lubricating eye drops for the treatment of dry eye signs and symptoms.

NCT ID: NCT00496236 Completed - Clinical trials for Head and Neck Cancer

Radiotherapy, Cetuximab, and Injections of TNFeradeā„¢ Biologic for Elderly or Frail Patients With Head and Neck Cancer

Start date: n/a
Phase: Phase 1/Phase 2
Study type: Interventional

This study is looking at the safety and tolerability of TNFeradeä Biologic combined with conventional once daily radiation therapy in elderly or frail patients with new onset locally advanced head and neck tumors.

NCT ID: NCT00496535 Completed - Clinical trials for Head and Neck Cancer

A Study of TNFeradeā„¢ Biologic With Concomitant Radiotherapy, Fluorouracil, and Hydroxyurea (TNF-FHX) in Patients With Head and Neck Cancer

Start date: n/a
Phase: Phase 1/Phase 2
Study type: Interventional

The primary objective of the first phase is to determine the safety, the maximum tolerated dose (MTD) and dose-limiting toxicity of TNFerade in combination with the previously studied combination of Fluorouracil (5FU), Hydroxyurea (HU) and standard daily radiotherapy in patients with recurrent head and neck cancer (RHNC). All chemoradiotherapy is administered on a "week-on/week-off" schedule. The primary objective of the second phase II is to determine the locoregional control rate at 24 months.

NCT ID: NCT00497263 Completed - Colorectal Cancer Clinical Trials

End-to-End Compression Anastomosis for Left-sided Colectomy Endo-CAR Study

Start date: n/a
Phase: Phase 2
Study type: Interventional

the purpose of this study is to evaluate the safety and effectiveness of the Niti CAR-device in the creation of colorectal anastomosis

NCT ID: NCT00500630 Completed - Clinical trials for Glenohumeral Osteoarthritis

Objective Evaluation of Shoulder Pathology and Surgery

Start date: n/a
Phase: N/A
Study type: Interventional

The goal of this study was to clinically validate a new device for the objective outcome evaluation of adult patients undergoing shoulder surgery for glenohumeral osteoarthritis and rotator cuff disease, using the activities of daily living described in the Simple Shoulder Test (SST) as a reference. The study was set up as a clinical trial including patients over an observation period of one year and a control group of subjects. Clinical evaluations will be made at baseline, 3 months, 6 months and 1 year after surgery by two independent observers. Miniature sensors each containing three 3D gyroscopes and three 3D accelerometers will allow computing new kinematic scores. They will be compared to the regular SST, DASH, ASES and Constant scores.

NCT ID: NCT00501579 Completed - Uveitis Clinical Trials

Study of Difluprednate in the Treatment of Uveitis

Start date: n/a
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the safety and efficacy of difluprednate compared with prednisolone acetate in the treatment of endogenous anterior uveitis.

NCT ID: NCT00502073 Completed - Dry Eye Syndromes Clinical Trials

Study of Cyclosporine in the Treatment of Dry Eye Syndrome (ST-603-005)

Start date: n/a
Phase: Phase 3
Study type: Interventional

The purpose of this phase 3 study is to determine the safety and efficacy of cyclosporine in the treatment of dry eye syndrome.

NCT ID: NCT00505115 Completed - Blastocyst Clinical Trials

The Human Blastocyst Secretome and Implantome

Start date: n/a
Phase: N/A
Study type: Observational

The aim of this study is to identify the protein secretion and consumption profile of the human blastocyst (secretome) and the implanted blastocyst (implantome) using the protein array technology.

NCT ID: NCT00505817 Completed - Clinical trials for Effect of Two Protocols of Ovarian Stimulation on Oocyte Quality

GnRH Agonist and Antagonists in an Oocyte Donation Program

Start date: n/a
Phase: Phase 4
Study type: Interventional

The primary purpose of this study is to evaluate the effect of the two different protocols (long protocol vs antagonist protocol) on oocyte / embryo quality.

NCT ID: NCT00508768 Completed - Clinical trials for Rheumatoid Arthritis

A Study of Oral SCIO-469 Pharmacokinetics (Study of a Drug in the Body to Watch How the Drug is Absorbed, Distributed, Metabolized and Eliminated Over a Period of Time) in the Body of Female Patients With Active Rheumatoid Arthritis

Start date: n/a
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the pharmacokinetics of two oral dosing regimens of SCIO-469, with and without methotrexate, in patients with active rheumatoid arthritis.