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Chronic Bronchitis clinical trials

View clinical trials related to Chronic Bronchitis.

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NCT ID: NCT05868941 Active, not recruiting - COPD Clinical Trials

Efficacy and Safety of Broncho Muco Cleaner Balloon Dilation Therapy

EXERTION
Start date: February 2, 2022
Phase: N/A
Study type: Interventional

In COPD patients with chronic bronchitis, it is aimed to determine whether the broncho muco cleaner balloon dilation method can provide clinical and functional benefit by causing destruction in hyperplasic goblet cells in the bronchial system. Although 2 studies have been published on this subject before, one of them is a retrospective design and the other is a pilot study consisting of only 10 patients . Therefore, it is clear that it should be supported by a controlled prospective study with more patients. Within the scope of the research, broncho muco cleaner balloon dilatation treatment will be performed with fiberoptic bronchoscope under general anesthesia in chronic bronchitis-predominant COPD cases, and the effectiveness and reliability of the procedure will be evaluated.

NCT ID: NCT05649046 Active, not recruiting - Lung Cancer Clinical Trials

Structuring of a Lung Cancer Screening Program Including Clinical, Radiological and Biological Phenotyping Useful for the Development of Individualized Risk Prediction Tools: PREVALUNG ETOILE

PREVALUNG*
Start date: January 23, 2023
Phase: N/A
Study type: Interventional

Patients treated at the Hôpital Nord de Marseille for at least one smoking-related pathology (atheroma, chronic bronchitis, non-progressive cancer > 5 years) or with eligibility criteria for lung cancer screening (inclusion criteria in the NLST or NELSON studies or American recommendations) Interventional study with minimal risks and constraints, with evaluation of lung cancer prevalence; immunological, blood inflammatory and microbiota profile Determine the maximum clinical, radiological, and biological phenotyping completeness rate following the implementation of a new lung cancer screening care pathway with multidimensional clinical, radiological, and biological phenotyping capabilities

NCT ID: NCT04677465 Active, not recruiting - Chronic Bronchitis Clinical Trials

Clinical Study of the RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic Bronchitis

RheSolve
Start date: April 7, 2021
Phase: N/A
Study type: Interventional

This is a prospective, randomized, parallel group, double-blind, sham-controlled, multicenter clinical trial following patients to 2 years. The objective is to assess the safety and effectiveness of Bronchial Rheoplasty for the treatment of the symptoms of chronic bronchitis in adult COPD patients with moderate to severe chronic bronchitis. A total of 270 patients will be randomized at up to 40 study centers in the United States, Canada, and Europe.

NCT ID: NCT04613180 Active, not recruiting - Acute Bronchiolitis Clinical Trials

Evaluation of the Effectiveness of Montelukast in Children With Recurrent Obstructive Bronchitis

Start date: January 3, 2018
Phase: Phase 4
Study type: Interventional

The aim of the study was to evaluate the effectiveness of montelukast sodium in the treatment and prevention of recurrent obstructive bronchitis in children. The investigators examined 80 children aged 1 to 7 years with recurrent obstructive bronchitis, who were randomly divided into 2 groups.

NCT ID: NCT04260555 Active, not recruiting - Acute Bronchitis Clinical Trials

Clinical Trial to Evaluate the Efficacy and Safety of 'DW1601' in Acute Bronchitis

Start date: December 20, 2018
Phase: Phase 3
Study type: Interventional

A Multicenter, Randomized, Double-Blind, Parallel, Active-controlled, Superiority, Phase III Clinical Trial to Evaluate the Efficacy and Safety of DW1601 Compared to DW16011 and DW16012 for Acute Bronchitis

NCT ID: NCT03892694 Active, not recruiting - COPD Clinical Trials

Metered Cryospray for the Treatment of Patients With Chronic Obstructive Pulmonary Disease With Chronic Bronchitis

Start date: February 14, 2020
Phase: N/A
Study type: Interventional

To evaluate the relationship between airway structure and function in patients with chronic bronchitis treated with metered cryospray (MCS).

NCT ID: NCT03631472 Active, not recruiting - Chronic Bronchitis Clinical Trials

Gala Early Feasibility Study of RheOx

Gala_EFS
Start date: July 6, 2018
Phase: N/A
Study type: Interventional

An early feasibility study (EFS) to assess the safety and clinical utility of RheOx on patients with chronic bronchitis in the United States.

NCT ID: NCT02627872 Active, not recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Clinical & Systems Medicine Investigations of Smoking-related Chronic Obstructive Pulmonary Disease

COSMIC
Start date: March 2007
Phase:
Study type: Observational

Chronic Obstructive Pulmonary Disease (COPD) is an increasing global health problem, which primarily increases among the female population. The purpose of this study is to perform in-depth clinical and molecular characterizations of early stage COPD patients, as well as healthy never-smoker and at-risk smoking control populations to identify molecularly related subgroups patients, including gender-related sub-phenotypes of COPD.

NCT ID: NCT02154568 Active, not recruiting - Healthy Clinical Trials

Study of Airflow in the Lungs Using Helium MRI

Start date: November 2013
Phase: N/A
Study type: Interventional

Computer simulations are being developed to predict air flow abnormalities in the airways of patients with lung disease. The purpose of this study is to obtain actual gas flow measurements in the lungs of healthy patients and patients with lung disease and use these measurements to validate the computer models.

NCT ID: NCT02087761 Active, not recruiting - Pneumonia Clinical Trials

A Multi-Site Clinical Evaluation of the ARIES Flu Assay in Symptomatic Patients

Start date: December 2015
Phase: N/A
Study type: Observational

The ARIES Flu Assay is a real-time PCR based qualitative assay for the direct detection and differentiation of respiratory viral nucleic acid in nasopharyngeal swabs specimens. The objective of this study is to establish the diagnostic accuracy of ARIES Flu Assay.