Clinical Trials Logo

Breast Surgery clinical trials

View clinical trials related to Breast Surgery.

Filter by:
  • Completed  
  • Page 1 ·  Next »

NCT ID: NCT05560633 Completed - Breast/Surgery Clinical Trials

Nipple-sparing Mastectomy in Combined With Buried Flap Monitoring

Start date: May 1, 2015
Phase:
Study type: Observational

1. Learning curve of ms-Tram and DIEP breast reconstructions surgery are important to guide the training of new surgeon. 2. Buried flap post operative monitoring without implantable doppler was seldom studied, a validated protocol reported. 3. The complication rates of the flap and oncological safety were studied.

NCT ID: NCT04895072 Completed - Postoperative Pain Clinical Trials

Injection Rate and Erector Spinae Plane Block

Start date: May 17, 2021
Phase: N/A
Study type: Interventional

To evaluate the effect of injection rate on the block sensory level in the ESP block.

NCT ID: NCT04827030 Completed - Breast Surgery Clinical Trials

ER-One: A Double-blind Trial of Erector Spinae Block (ESP) Versus Paravertebral Block (PVB) Before Breast Cancer Surgery

ER-One
Start date: June 28, 2021
Phase: Phase 4
Study type: Interventional

The block (ESP or PVB) will be performed preoperatively in the recovery room under standard monitoring. After setting a peripheral venous access, patient will be installed on lateral decubitus position on the opposite side of the block.

NCT ID: NCT04742309 Completed - Breast Surgery Clinical Trials

Pectoralis Block vs Paravertebral Nerve Blocks for Breast Surgery

Start date: February 25, 2021
Phase: Phase 4
Study type: Interventional

Following painful surgical procedures of the breast, postoperative analgesia is often provided with a nerve block called a "paravertebral" block. For intense, but shorter-duration acute pain, a single-injection of numbing medicine is used which lasts about 12 hours. Recently, a new type of block has been reported: the "Pecs-2" block. The theoretical benefits include ease of administration since it is closer to the skin (less deep) compared with the paravertebral block and therefore easier to identify and target with ultrasound (therefore increasing success rate); and, a lower risk of complications. Lastly, it might be easier to insert a tiny tube which would allow additional numbing medicine to be injected. There are, therefore, multiple theoretical reasons to prefer the Pecs-2 over the paravertebral nerve block. Unfortunately, it remains unknown if the pain control provided by this new type of block is comparable to that provided with the older block. The investigators therefore propose to compare these two blocks with a clinical study.

NCT ID: NCT04457115 Completed - Opioid Use Clinical Trials

Erector Spinae Plane Block Versus Thoracic Paravertebral Block for Pain Control in Modified Radical Mastectomy

Start date: April 27, 2020
Phase: N/A
Study type: Interventional

The aim of the study is to compare the effectiveness of the Erector spinae plane (ESP) block versus thoracic paravertebral (TPV) block in the post-operative pain control after radical mastectomy.

NCT ID: NCT04254679 Completed - Abdominal Surgery Clinical Trials

Pilot Trial: Postoperative Opioid-free Analgesia

Start date: January 29, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

North America is facing an opioid epidemic fueled by surgeons, who are the second largest subgroup of physicians involved in opioid prescribing. Surgery often serves as the initial event for opioid-naïve patients to obtain a prescription for opioids and spiral into misuse and addiction. From the perspective of perioperative care clinicians, the answer to the opioid crisis may be using opioid-free analgesia. However, the number of comparative studies in this field is limited and existing small trials do not reflect current standards of care in North America. Lack of evidence means that the decision to prescribe opioids after outpatient surgery largely depends on surgeon preference and healthcare culture. Hence, there is an urgent need for a robust randomized controlled trial (RCT) to guide clinical decision-making. The feasibility and optimal design of this RCT should be informed by a pilot trial. The overarching goal of this pilot RCT is to investigate the feasibility of conducting a full-scale RCT to assess the comparative-effectiveness of opioid versus opioid-free analgesia after outpatient general surgery.

NCT ID: NCT04166279 Completed - Breast Cancer Clinical Trials

The Recovery of Reaching Movement in Breast Cancer Survivors: Two Different Rehabilitative Protocols in Comparison

Start date: January 8, 2018
Phase: N/A
Study type: Interventional

This study emphasizes the importance of rehabilitation in breast cancer survivors after mastectomy, even during the course of radiotherapy and chemotherapy, both for good efficacy in reducing pain and for functional recovery of the upper limb. Authors designed a randomized-controlled trial to compare two different rehabilitation protocols: the single rehabilitative treatment (ST) and the group treatment (GT). The study is the first attempt to measure the reaching movement after BC surgery with an optoelectronic evaluation system previously standardized in the neurological field during rehabilitation treatment.

NCT ID: NCT04036370 Completed - Postoperative Pain Clinical Trials

Continuous Pectoral Nerve Block in Breast Cancer Surgery

Start date: July 30, 2019
Phase: N/A
Study type: Interventional

The purpose of the study is to evaluate the effect of continuous pectoral nerve block on postoperative analgesia consumption in breast cancer surgery.

NCT ID: NCT03860974 Completed - Breast Surgery Clinical Trials

Serratus Plane Versus Paravertebral Nerve Blocks for Breast Surgery

Start date: May 9, 2019
Phase: Phase 4
Study type: Interventional

Following painful surgical procedures of the breast, postoperative analgesia is often provided with a paravertebral nerve block (PVB). For intense, but shorter-duration acute pain, a single-injection of local anesthetic is used with a duration of approximately 12 hours. Recently an alternative block has been reported: the serratus plane block.2 The theoretical benefits include ease of administration since it is a plane superficial to the PVB and therefore easier to identify and target with ultrasound (therefore increasing success rate); and an increased safety margin as there are fewer anatomic structures in the immediate area which could be injured with the needle; and, the target plane is much further from the intrathecal/epidural space relative to the PVB, therefore leakage of cerebrospinal fluid or injury to the spinal cord are less likely with the serratus compared to the PVB.3 There are, therefore, multiple theoretical reasons to prefer the serratus over the PVB. Unfortunately, it remains unknown if the analgesia provided by this new technique is comparable to that provided with the PVB.4 The investigators therefore propose to compare these two techniques with a randomized, subject-masked, active-controlled, parallel-arm clinical trial.

NCT ID: NCT03857386 Completed - Postoperative Pain Clinical Trials

Efficacy of Pectoral Nerve Block for Breast Reduction Surgery

Start date: July 1, 2017
Phase:
Study type: Observational

The purpose of the study is to evaluate the efficacy of PECS block applied to patients undergoing bilateral breast reduction surgery on postoperative analgesia compared to local infiltration anesthesia.