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Breast Neoplasms clinical trials

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NCT ID: NCT00161291 Completed - Breast Cancer Clinical Trials

Open Label Trial for Post-Menopausal Women With Newly Diagnosed Operable Breast Cancer

Start date: June 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine pathological response to a maximum of 18 weeks of neoadjuvant therapy using a combination of letrozole and Bevacizumab in post-menopausal women with pathologically confirmed invasive ductal cancer or invasive lobular cancer of the breast whose tumors are hormone positive.

NCT ID: NCT00161265 Completed - Breast Cancer Clinical Trials

Tissue Procurement Protocol for Patients Undergoing Neoadjuvant Systemic Therapy for Breast Cancer

Start date: May 2005
Phase: N/A
Study type: Observational

This study is being performed so that tumor and blood samples from patients who will receive breast cancer treatment prior to surgery can be collected and stored for future research.

NCT ID: NCT00160901 Completed - Breast Cancer Clinical Trials

Complementary Therapies for the Reduction of Side Effects During Chemotherapy for Breast Cancer

Start date: August 2003
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine wether a complementary therapy consisting of a combined medication of selenium, milk thistle, goldenrod and bromelain and a consultation concerning nutrition and physical activity can reduce side effects of a chemotherapy in breast cancer patients.

NCT ID: NCT00159458 Terminated - Clinical trials for Recurrent Breast Cancer

Clinical Trial of Gemcitabine and Oxaliplatin in Recurrent or Metastatic Breast Cancer

Start date: July 2003
Phase: Phase 2
Study type: Interventional

The purpose of this study is to find out if the combination of gemcitabine and oxaliplatin chemotherapy will be effective in reducing or eliminating the tumor(s) in patients with recurrent or metastatic breast cancer. Gemcitabine is a chemotherapy drug approved by the U.S. Food and Drug Administration (FDA) for the treatment of pancreatic and lung cancer; oxaliplatin is a chemotherapy drug that is approved by the FDA for the treatment of colon cancer. Neither gemcitabine nor oxaliplatin are approved for the treatment of breast cancer. However, both drugs have been shown to decrease the size of breast cancer tumors.

NCT ID: NCT00159094 Recruiting - Clinical trials for Metastatic Breast Cancer

A Trial of Doxil and Multiday Vinorelbine in Patients With Metastatic Breast Cancer

Start date: October 2003
Phase: Phase 2
Study type: Interventional

This is a phase II trial of Doxil on day 1 and vinorelbine on days 1 and 2 in women with metastatic breast cancer. Administered every 28 days. A study to assess the safety and efficacy of Doxil and vinorelbine in metastatic breast cancer.

NCT ID: NCT00156806 Completed - Breast Cancer Clinical Trials

Investigating the Therapeutic Effectiveness of Aloe Barbadensis in Reducing Cutaneous Side-Effects of Radiation Treatment for Breast Cancer.

Start date: March 2002
Phase: Phase 3
Study type: Interventional

Breast cancer treatment often involved radiation to the breast. A side-effect of this treatment is skin redness, itching and burning. Some patients have quite severe reactions. Our current treatment for this is to avoid any soaps or other skin irritants and to use a moisturizing cream once all radiation is finished. Aloe vera is believed by many people to be useful for treatment of skin burns but this has never been proven in a randomized study. The aim of this study is to compare aloe vera gel versus plan gel versus the standard treatment to determine if there is any benefit. If there was a benefit of gel treatment over standard it could make radiation treatments more tolerable for cancer patients.

NCT ID: NCT00156312 Completed - Breast Cancer Clinical Trials

Evaluation of Tumor Factors in Breast Cancer Treated With Docetaxel and Capecitabine

Start date: July 2003
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether the combination of the drugs docetaxel and capecitabine is effective in treating breast cancer patients.

NCT ID: NCT00156273 Completed - Clinical trials for Metastatic Breast Cancer

Determine Feasibility of Quantifying Apoptosis and Bcl-2 Expression in CTCs in Women With Metastatic Breast Cancer

Start date: April 2005
Phase: N/A
Study type: Observational

We are trying to develop better ways to detect when cancer therapies are working.

NCT ID: NCT00156260 Terminated - Breast Cancer Clinical Trials

Feasibility Study of Evaluating Breast Cancer Patients With Ductal Lavage

Start date: January 2003
Phase: N/A
Study type: Observational

The primary purpose of this research is to analyze the cells present in the fluid obtained via ductal lavage from the nipple of a woman with a known diagnosis of breast cancer. A portion of the lavage fluid may be used in future breast cancer biomarkers. Remaining lavage fluid will be used to analyze its biochemical composition, for investigational purposes only.

NCT ID: NCT00156130 Completed - Breast Cancer Clinical Trials

Accelerated Radiotherapy Outcomes in Women

Start date: October 2003
Phase: Phase 4
Study type: Observational

This study is evaluating the long-term outcomes of women in a randomized trial that compared accelerated whole breast irradiation (42.5 Gy in 16 fractions over 22 days) to a longer conventional schedule of whole breast irradiation (50 Gy in 25 fractions over 35 days) following breast-conserving surgery. The outcomes evaluated will include cosmetic outcome and cardiac disease as a measure of late radiation morbidity and local breast recurrence as a measure of effectiveness.