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Breast Neoplasms clinical trials

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NCT ID: NCT00892268 Terminated - Breast Cancer Clinical Trials

Acupuncture or Medication in Reducing Pain in Postmenopausal Women With Breast Cancer and Joint Pain

Start date: January 2008
Phase: Phase 2
Study type: Interventional

RATIONALE: Acupuncture may reduce joint pain in postmenopausal women with breast cancer. It is not yet known whether acupuncture is more effective than standard therapy analgesics in decreasing joint pain caused by aromatase inhibitors. PURPOSE: This randomized phase II trial is studying acupuncture to see how well it works compared with medication in reducing pain in postmenopausal women with breast cancer and joint pain.

NCT ID: NCT00891969 Terminated - Breast Cancer Clinical Trials

Treatment Decision Making Between Oncologists and Women With Newly Diagnosed Breast Cancer and Their Healthy Companions

Start date: February 2009
Phase: Phase 1
Study type: Observational

RATIONALE: A study that looks at communication between patients and doctors may help oncologists improve patient satisfaction with their treatment plan. PURPOSE: This phase I trial is studying treatment decision making between oncologists and women with newly diagnosed breast cancer and their healthy companions.

NCT ID: NCT00891800 Terminated - Clinical trials for Breast Cancer Metastatic to the Liver

Brachytherapy Radiation Directly to the Liver in Breast Cancer Patients With Metastatic to Liver

SIRT
Start date: July 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study to study whether or not the use of direct radiation therapy with Y-90 microspheres (SIR-Spheres) has any effect on treated liver with respect to tumor response in breast cancer patients. Criteria: - Breast cancer - Clinical evidence of metastatic disease in the liver - Performance status (0-2) - Not pregnant - Laboratory values received after any prior chemotherapy - Normal Pt/PTT - recovered from any chemotherapy side-effects - No prior radiation therapy to the liver - No other MAJOR site of cancer such as lungs or brain - No uncontrolled infections - a candidate for surgical resection or ablation therapy

NCT ID: NCT00891280 Recruiting - Breast Cancer Clinical Trials

Dose-escalation Study of Oral CX-4945

Start date: February 2009
Phase: Phase 1
Study type: Interventional

This Phase 1 study of oral CX-4945 is designed to test the safety, tolerability and highest safe dose level of this CK2 inhibitor in patients with advanced solid tumor cancers, Castleman's Disease or Multiple Myeloma.

NCT ID: NCT00890903 Completed - Clinical trials for Metastatic Breast Cancer

Non-Interventional Study With Vinorelbine ORAL in Advanced Non-Small Cell Lung Carcinoma(NSCLC) and Metastatic Breast Cancer (MBC)

Start date: March 2009
Phase: N/A
Study type: Observational

The purpose of this non-interventional study is to collect data on efficacy and toxicity of the use of Navelbine ORAL in daily routine in Germany (especially after availability of an 80mg capsule). The study focusses on concomitant antiemetic therapy and patient compliance.

NCT ID: NCT00888082 Withdrawn - Breast Cancer Clinical Trials

Protection of Ovarian Function With Goserelin Acetate in Premenopausal Early Breast Cancer Patients With Chemotherapy

PROOF
Start date: n/a
Phase: Phase 3
Study type: Interventional

Primary objective of this study is to determine the effectiveness of goserelin acetate (Zoladex) in preserving ovarian function in premenopausal women undergoing adjuvant chemotherapy for primary invasive breast cancer by documenting persistence or resumption of regular menses via menstrual history, serum FSH and E2 measurements. The secondary objectives of this study are as follows: To investigate the impact of treatment with chemotherapy with or without goserelin acetate (i.e. impact of the expectation of ovarian function preservation) on participants' quality of life (QOL) by FACT-ES scale, and to compare safety and tolerability of study drugs in two treatment groups by evaluation of adverse events.

NCT ID: NCT00887692 Completed - Breast Carcinoma Clinical Trials

Comparison of Set-up Reproducibility Between Prone and Supine Intensity Modulated Radiotherapy (IMRT) for the Adjuvant Treatment of Breast Carcinoma After Lumpectomy

Start date: July 2009
Phase: N/A
Study type: Interventional

10 patients will be treated alternating daily between prone and supine position for breast radiotherapy to compare set-up accuracy. Prone treatment will be given on the odds days and supine treatment on the even days.

NCT ID: NCT00887575 Completed - Breast Cancer Clinical Trials

Neoadjuvant Sunitinib With Paclitaxel/Carboplatin in Patients With Triple-Negative Breast Cancer

Start date: June 2009
Phase: Phase 1/Phase 2
Study type: Interventional

This trial will examine the combination of sunitinib plus paclitaxel and carboplatin as neoadjuvant treatment for locally advanced breast cancer.

NCT ID: NCT00887536 Completed - Breast Cancer Clinical Trials

A Clinical Trial Comparing the Combination of TC Plus Bevacizumab to TC Alone and to TAC for Women With Node-Positive or High-Risk Node-Negative, HER2-Negative Breast Cancer

Start date: May 2009
Phase: Phase 3
Study type: Interventional

The main purpose of this study is to learn if adding bevacizumab to standard treatment with chemotherapy (docetaxel, doxorubicin, and cyclophosphamide) for early stage HER2-negative breast cancer will prevent breast cancer from returning. A second purpose of this study is to learn if adding bevacizumab to treatment with chemotherapy will help women with HER2-negative breast cancer live longer. The researchers also want to learn about the side effects of the combination of drugs used in this study.

NCT ID: NCT00887523 Completed - Breast Carcinoma Clinical Trials

Trial Comparing Prone and Supine Intensity-modulated Radiotherapy (IMRT) After Breast-conserving Surgery in Patients With Large Breast Volume at High Risk for Skin Toxicity and Fibrosis

Start date: July 2009
Phase: N/A
Study type: Interventional

84 patients with a cup size C or more will be randomized to receive intensity-modulated radiotherapy in supine or prone position.