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Breast Neoplasms clinical trials

View clinical trials related to Breast Neoplasms.

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NCT ID: NCT00156806 Completed - Breast Cancer Clinical Trials

Investigating the Therapeutic Effectiveness of Aloe Barbadensis in Reducing Cutaneous Side-Effects of Radiation Treatment for Breast Cancer.

Start date: March 2002
Phase: Phase 3
Study type: Interventional

Breast cancer treatment often involved radiation to the breast. A side-effect of this treatment is skin redness, itching and burning. Some patients have quite severe reactions. Our current treatment for this is to avoid any soaps or other skin irritants and to use a moisturizing cream once all radiation is finished. Aloe vera is believed by many people to be useful for treatment of skin burns but this has never been proven in a randomized study. The aim of this study is to compare aloe vera gel versus plan gel versus the standard treatment to determine if there is any benefit. If there was a benefit of gel treatment over standard it could make radiation treatments more tolerable for cancer patients.

NCT ID: NCT00156312 Completed - Breast Cancer Clinical Trials

Evaluation of Tumor Factors in Breast Cancer Treated With Docetaxel and Capecitabine

Start date: July 2003
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether the combination of the drugs docetaxel and capecitabine is effective in treating breast cancer patients.

NCT ID: NCT00156273 Completed - Clinical trials for Metastatic Breast Cancer

Determine Feasibility of Quantifying Apoptosis and Bcl-2 Expression in CTCs in Women With Metastatic Breast Cancer

Start date: April 2005
Phase: N/A
Study type: Observational

We are trying to develop better ways to detect when cancer therapies are working.

NCT ID: NCT00156130 Completed - Breast Cancer Clinical Trials

Accelerated Radiotherapy Outcomes in Women

Start date: October 2003
Phase: Phase 4
Study type: Observational

This study is evaluating the long-term outcomes of women in a randomized trial that compared accelerated whole breast irradiation (42.5 Gy in 16 fractions over 22 days) to a longer conventional schedule of whole breast irradiation (50 Gy in 25 fractions over 35 days) following breast-conserving surgery. The outcomes evaluated will include cosmetic outcome and cardiac disease as a measure of late radiation morbidity and local breast recurrence as a measure of effectiveness.

NCT ID: NCT00156052 Completed - Breast Cancer Clinical Trials

Hypofractionated Radiotherapy Post-Lumpectomy in Women With Node Negative Breast Cancer

Start date: April 1993
Phase: N/A
Study type: Interventional

To determine if hypofractionated radiotherapy to the whole breast (4,250 cGy/16 fractions over 22 days) is equally effective to standard fractionated radiotherapy (5,000 cGy/25 fractions over 35 days) in women with node negative breast cancer who have undergone lumpectomy. The primary outcome is local breast recurrence and secondary outcomes include morbidity and cost effectiveness.

NCT ID: NCT00156039 Completed - Breast Cancer Clinical Trials

Randomized Trial of Follow-up Strategies in Breast Cancer

Start date: January 1997
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether family physician 'routine follow-up care' of women with breast cancer in remission is an acceptable alternative to the existing system of specialist follow-up. Primary outcome measure are event rates of oncological catastrophes and quality of life.

NCT ID: NCT00155259 Completed - Breast Cancer Clinical Trials

Docetaxel, Cisplatin and Capecitabine as Neoadjuvant Chemotherapy for Locally Advanced Breast Cancer

Start date: October 2004
Phase: Phase 2
Study type: Interventional

The primary endpoint of this phase II trial is the objective response rate of the regimen. The secondary endpoints include treatment-related toxicity, progression free survival and overall survival and breast conserving rate.

NCT ID: NCT00153907 Completed - Breast Cancer Clinical Trials

Navelbine and Capecitabine in the Treatment of Metastatic Breast Cancer

Start date: March 2002
Phase: Phase 1
Study type: Interventional

The purpose of this study is to find the highest dose of capecitabine and oral navelbine that can be given without causing severe side effects, and to determine the safety, tolerability, and effects (good and bad) of capecitabine given with oral navelbine to patients with advanced breast cancer.

NCT ID: NCT00153894 Completed - Breast Cancer Clinical Trials

Effects of Exercise Intervention on Insulin Levels in Breast Cancer Survivors

Start date: December 2003
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether an exercise program comprised of strength and endurance training will lower fasting insulin levels in a group of breast cancer survivors. Insulin may be involved in the risk of breast cancer recurrence.

NCT ID: NCT00153218 Completed - Breast Cancer Clinical Trials

An Observational Study of Current Practice Pattern on the Treatment of Women With Metastatic Breast Cancer Whose Tumors Overexpress Her2neu

Start date: June 2004
Phase: N/A
Study type: Observational

The purpose of this study is to observe clinical outcomes of metastatic breast cancer patients whose tumors overexpress the Her2neu protein and are being treated with trastuzumab (Herceptin)either alone or combination with chemotherapy or hormonal therapy.