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Breast Neoplasms clinical trials

View clinical trials related to Breast Neoplasms.

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NCT ID: NCT04688762 Completed - Breast Cancer Clinical Trials

The E-consult Application for Patients With Breast Cancer: Interest in Empathy and Empowerment of Patients.

e-CONSULT
Start date: December 24, 2020
Phase:
Study type: Observational

Demonstrate that the use of this application in consultation could improve the empathy perceived of the doctors by the patients after the consultation.

NCT ID: NCT04688086 Completed - Breast Cancer Clinical Trials

A Prospective Study to Evaluate Clinical Performance of Thermalytix in Detecting Breast Cancers

Start date: December 15, 2018
Phase:
Study type: Observational

The purpose of this study is to determine the clinical performance of AI-based Thermalytix with the current standard-of-care diagnostic modalities in women.

NCT ID: NCT04679207 Completed - Breast Cancer Clinical Trials

A Pilot Study of Ultrasound-guided Vacuum-assisted Excision of Breast Cancers

PICASSO
Start date: June 25, 2018
Phase:
Study type: Observational

This study is looking into whether the procedure called Vacuum Assisted Excision (VAE) is a safe method for the removal of small and medium sized invasive breast cancers in patients who are unfit or have refused to have surgery to remove cancer. Recruitment Target: 20

NCT ID: NCT04678544 Completed - Neoplasm, Breast Clinical Trials

Cooling Cap Trial to Prevent Permanent Chemotherapy-induced Alopecia in Breast Cancer Patients

Start date: December 23, 2020
Phase: N/A
Study type: Interventional

This study aims to examine whether the PSCS2 is effective in reducing chemotherapy-induced alopecia in woman with breast cancer undergoing neoadjuvant or adjuvant chemotherapy. Female adults who are newly diagnosed with stage 1-3 breast cancer and expected to receive Adriamycin or/and Taxane will participate in the study. The study design is a open label, randomized controlled trial. The patients will be randomly assigned to intervention or control groups. Intervention patients will have applied scalp cooling during 4 or 6 cycles of their chemotherapy. Primary endpoint is the effectiveness of the PSCS2 for reducing permanent chemotherapy-induced alopecia. Secondary endpoints include chemotherapy-induced alopecia, distress due to chemotherapy induced alopecia, quality of life, and patient-reported alopecia related side effect.

NCT ID: NCT04677075 Completed - Breast Neoplasms Clinical Trials

New Formula to Predict the Need for Reconstructive Coverage Following Mastectomy

Start date: August 15, 2020
Phase:
Study type: Observational

Mastectomy is a cornerstone operative procedure in breast cancer treatment leaving a raw area behind with possibility of failure of primary closure sometimes with unavailability of facilities of reconstruction. This opened the door for this research to find a formula to predict the need of reconstruction

NCT ID: NCT04676516 Completed - Breast Cancer Clinical Trials

A Phase II Window of Opportunity Trial of PRMT5 Inhibitor, GSK3326595, in Early Stage Breast Cancer

OTT-19-06
Start date: June 8, 2021
Phase: Phase 2
Study type: Interventional

This is a Phase II Randomized Window of Opportunity Trial Evaluating Clinical and Biological effects of PRMT5 inhibitor, GSK3326595, in Early Stage Breast Cancer

NCT ID: NCT04676438 Completed - Pain, Postoperative Clinical Trials

Persistant Post-mastectomy Pain in Breast Cancer : Incidence and Risk Factors

Start date: December 10, 2018
Phase:
Study type: Observational

Post Mastectomy Pain Syndrome (PMPS) is a major complication of breast surgery responsible for depression and disability. The project consists of a prospective cohort on patients going for oncological breast surgery at National Institute of Oncology of Rabat. Chronic postoperative pain (CPP) remains a disturbing and obscure clinical problem, which could last for more than 3 months after surgery. The aim of present study was to assess the prevalence of CPP, investigate its impact on life quality and explore its potential risk factors. After informed consent was signed, patients receiving surgery under general anesthesia in Peking Union Medical College Hospital and other medical centers participating in this study during 2018 will be included. Patients' preoperative information will be collected from medical record, including basic demographic data, primary disease and previous chronic diseases. Intraoperative information will be obtained from anesthesia record, including surgical scope, duration, length and location of incisions and blood loss. Acute pain will be evaluated in the ward of the department of surgery, when an app will be installed on patients' mobile phones. Our long-term postoperative follow-up would be performed by sending out survey questionnaires via this app in the 4th, 8th, 16th, 32th, and 48th weeks after surgery. The survey covers questions regarding the intensity, characteristic, location and impact on daily activities of CPP. Information regarding treatment of CPP will also be collected, if any. All the data gained will be summarized in our database and analyzed.

NCT ID: NCT04674852 Completed - Clinical trials for Breast Neoplasm Female

Mayo Designed Soft Tissue Ultrasound-Detectable Marker

Start date: November 2, 2020
Phase: N/A
Study type: Interventional

Researchers are trying to determine if the Mayo marker is easily seen with ultrasound making it easier, faster, and more accurate for preoperative localization of the biopsied positive lymph node.

NCT ID: NCT04667481 Completed - Breast Cancer Clinical Trials

Adaptive Training Exercise Programs for Improving Cardiorespiratory Fitness After Breast Cancer Treatment, The ACTIVATE Trial

ACTIVATE
Start date: January 5, 2022
Phase: N/A
Study type: Interventional

This clinical trial studies the feasibility of implementing various adaptive training exercise programs to improve cardiorespiratory fitness in patients after receiving breast cancer treatment. Information from this study may help researchers better understand how to implement adaptive training interventions to improve cardiorespiratory fitness in patients after receiving breast cancer treatment.

NCT ID: NCT04664972 Completed - Clinical trials for Triple Negative Breast Cancer

Comparison of TP and TAC Regimens in Neoadjuvant Treatment of TNBC

Start date: November 23, 2018
Phase: Phase 2
Study type: Interventional

Previous studies have shown that TNBC is sensitive to DNA crosslinking-related chemotherapeutic drugs such as platinum. However, there is a lack of large sample prospective clinical data to compare the efficacy of TP and EC-T / TEC regimen in the neoadjuvant chemotherapy of TNBC. Besides, the application of anthracycline drugs is limited to a certain extent due to the cardiotoxicity. Based on the above evidence, the researchers hope to explore a more effective and safer new adjuvant therapy for TNBC.