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Breast Neoplasms clinical trials

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NCT ID: NCT00645177 Completed - Clinical trials for Metastatic Breast Cancer

Phase 2 Study of ABT-869 in Combination With Paclitaxel Versus Paclitaxel Alone to Treat Metastatic Breast Cancer

Start date: July 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the effect of ABT-869 plus paclitaxel compared to paclitaxel alone on disease progression in metastatic breast cancer.

NCT ID: NCT00645138 Completed - Breast Cancer Clinical Trials

Comparison of Paravertebral Block With General Anesthesia in Patients Undergoing Breast Cancer Surgery

Start date: April 2008
Phase: Phase 3
Study type: Interventional

The purpose of this project is to determine if there is a difference between paravertebral block and general anesthesia in terms of time to discharge from the Post-Anesthesia Care Unit and pain level in patients undergoing outpatient breast cancer surgery.

NCT ID: NCT00643513 Completed - Breast Cancer Clinical Trials

Quality Of Life While Receiving Faslodex

Start date: June 2007
Phase: N/A
Study type: Observational

To study QoL related response, symptom spectrum and severity in disseminated breast cancer patients receiving Faslodex hormonal therapy.

NCT ID: NCT00641303 Completed - Breast Cancer Clinical Trials

Acupuncture in Reducing Muscle and Bone Symptoms in Women Receiving Letrozole, Exemestane, or Anastrozole for Stage 0, Stage I, Stage II, or Stage III Breast Cancer

Start date: May 2008
Phase: N/A
Study type: Interventional

RATIONALE: Acupuncture may help relieve muscle and bone pain caused by aromatase inhibitor therapy, such as letrozole, exemestane, and anastrozole. PURPOSE: This randomized phase II trial is studying acupuncture to see how well it works in reducing muscle and bone symptoms in women receiving letrozole, exemestane, or anastrozole for stage 0, stage I, stage II, or stage III breast cancer.

NCT ID: NCT00640861 Completed - Breast Cancer Clinical Trials

Vaccine Therapy in Treating Patients With Previously Treated Stage II or Stage III Breast Cancer

Start date: August 28, 2008
Phase: Early Phase 1
Study type: Interventional

RATIONALE: Vaccines made from peptides may help the body build an effective immune response to kill tumor cells. It is not yet known which vaccine is most effective in treating breast cancer. PURPOSE: This randomized clinical trial is studying the side effects of three different vaccine therapies and comparing the vaccines to see how well they work in treating patients with previously treated stage II or stage III breast cancer.

NCT ID: NCT00639366 Completed - Breast Cancer Clinical Trials

Radiation Therapy to the Head in Preventing Brain Metastases in Women Receiving Trastuzumab and Chemotherapy for Metastatic or Locally Advanced Breast Cancer

Start date: February 2007
Phase: Phase 3
Study type: Interventional

RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. It is not yet known whether radiation therapy directed at the head is effective in preventing brain metastases in patients with advanced cancer. PURPOSE: This randomized phase III trial is studying radiation therapy to the head to see how well it works in preventing brain metastases in women receiving trastuzumab and chemotherapy for metastatic or locally advanced breast cancer.

NCT ID: NCT00639210 Completed - Clinical trials for Improve Quality of Life

BREAST CANCER AND EXERCISE

BREX
Start date: September 2005
Phase: Phase 3
Study type: Interventional

A Finnish Breast Cancer Group Study (BREX 01-2004). A multicenter phase III open randomised trial of the efficacy of exercise in the prevention of long-term adverse effects of adjuvant treatments and breast cancer recurrences in women with primary breast cancer. The aim of the study is to investigate whether regular exercise training could reduce the long-term side effects of adjuvant treatments of primary breast cancer and improve quality of life and well being.

NCT ID: NCT00639171 Completed - Breast Tumors Clinical Trials

Evaluate the Use of the Magnetic Resonance Spectroscopy in Determining if the Breast Tumor is Benign or Malignant

Start date: November 2005
Phase:
Study type: Observational

Magnetic Resonance Spectroscopy (MRS) is a novel imaging technique for noninvasive probing of biochemical properties of tissue. While MRS does not generate images of tumor per se it allows biochemical spectroscopic data to be obtained in vivo from user defined region-of-interest. In this manner, biochemical information elucidated by MRS can be interpreted in relation to detailed anatomy and images of metabolite distribution can be created. The aim of MRS is to identify presence and concentration of metabolites characteristic for normal and abnormal (tumor) cellular activities hence allow differential normal tissue from pathological tissue, as well as allow differentiating malignant from benign tumors.

NCT ID: NCT00638599 Completed - Breast Cancer Clinical Trials

Comparison of Laryngeal Mask Airway (LMA®) and Tracheal Tube in Modified Radical Mastectomy on Breast Cancer

LMATBBC
Start date: January 2008
Phase: Phase 4
Study type: Interventional

Airway management in anesthesia is critical to guarantee appropriate treatment of possible respiratory complications and successful operative practice. LMA® is an alternative to tracheal tube in some surgeries like as mastectomy on breast cancer. Given no need using muscular relaxants in mastectomy, the investigators hypothesized that LMA® would be a superior manner in airway management in radical modified mastectomy on breast cancer than the tracheal tube, and the LMA® might produce less influence on patients' circulatory homeostasis, and easier to be placed before operation.

NCT ID: NCT00638391 Completed - Breast Cancer Clinical Trials

Ax-003/Arimidex (Anastrozole) in the Adjuvant Therapy of Early Breast Cancer

Ax-003
Start date: May 2005
Phase: N/A
Study type: Observational

The purpose of this study is the initial/followed by 5 year adjuvant therapy with Anastrozole.