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Breast Neoplasms clinical trials

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NCT ID: NCT00681369 Completed - Breast Cancer Clinical Trials

Observational Usage Study of Faslodex in Patients Suffering From Initial Breast Cancer in France

Start date: May 2007
Phase: N/A
Study type: Observational

the purpose of this study is to describe the way Faslodex is used in France, in patients suffering from initial breast cancer, that is to evaluate Faslodex treatment duration and to determine patients profile

NCT ID: NCT00681304 Completed - Breast Cancer Clinical Trials

Ultrasound Based Localization of Lumpectomy Bed in Anatomical Coordinate System

Start date: August 2007
Phase: Phase 0
Study type: Observational

This is a pilot study. The main purposes for doing the study are to see if there is a relationship between lumpectomy volume and position as measured by USEI and by CT. This is not a study to see if the use of USEI is better than the current method of using CT for daily radiation therapy positioning.

NCT ID: NCT00680758 Completed - Breast Cancer Clinical Trials

Cisplatin, Paclitaxel, and Everolimus in Treating Patients With Metastatic Breast Cancer

Start date: May 2008
Phase: Phase 1
Study type: Interventional

RATIONALE: Drugs used in chemotherapy, such as cisplatin and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving more than one drug (combination chemotherapy) together with everolimus may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of cisplatin, paclitaxel, and everolimus when given together for the treatment of patients with metastatic breast cancer.

NCT ID: NCT00680667 Completed - Breast Cancer Clinical Trials

Clinical Trial of Trametes Versicolor in Women With Breast Cancer

Start date: April 2007
Phase: Phase 1
Study type: Interventional

RATIONALE: Coriolus versicolor mushroom extract may slow the growth of cancer cells and may be an effective treatment for breast cancer. PURPOSE: This phase I trial is studying the side effects and best dose of coriolus versicolor extract in treating women with stage I, stage II, or stage III breast cancer who have finished radiation therapy.

NCT ID: NCT00679783 Completed - Breast Cancer Clinical Trials

Phase II Study of AZD2281 in Patients With Known BRCA Mutation Status or Recurrent High Grade Ovarian Cancer or Patients With Known BRCA Mutation Status/ Triple Neg Breast Cancer

Start date: July 8, 2008
Phase: Phase 2
Study type: Interventional

This is a Phase II, open label, non randomized correlative study of AZD2281 in patients with recurrent breast and ovarian cancer in both BRCA inherited mutation carriers and non-carriers to identify objective response rate and to assess for early markers of activity and to assess correlative markers that may provide helpful information for subsequent clinical trials. Approximately 110 patients from 7 centers in Canada will be enrolled into this study

NCT ID: NCT00679341 Completed - Breast Cancer Clinical Trials

A Study of the Efficacy and Safety of Trastuzumab Emtansine (Trastuzumab-MCC-DM1) vs. Trastuzumab (Herceptin®) and Docetaxel (Taxotere®) in Patients With Metastatic HER2-positive Breast Cancer Who Have Not Received Prior Chemotherapy for Metastatic Disease

Start date: September 2008
Phase: Phase 2
Study type: Interventional

This was a Phase II, randomized, multicenter, international, 2-arm, open-label clinical trial designed to explore the efficacy and safety of trastuzumab emtansine (T-DM1) relative to the combination of trastuzumab and docetaxel in patients with human epidermal growth factor receptor 2 (HER2)-positive, unresectable, locally advanced breast cancer and/or metastatic breast cancer who have not received prior chemotherapy for metastatic disease.

NCT ID: NCT00679211 Completed - Clinical trials for Metastatic Breast Cancer

A Study of Trastuzumab-Mcc-DM1 Administered Intravenously to Patients With HER2-Positive Metastatic Breast Cancer

Start date: August 2008
Phase: Phase 2
Study type: Interventional

Study of trastuzumab emtansine (T-DM1) administered to patients with human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer.

NCT ID: NCT00679185 Completed - Breast Cancer Clinical Trials

Expressive Writing in Improving Quality of Life in Patients With Breast Cancer and Lymphedema

Start date: January 2007
Phase: N/A
Study type: Interventional

RATIONALE: Expressive writing may help relieve symptoms and improve quality of life in breast cancer survivors with chronic lymphedema. PURPOSE: This clinical trial is studying expressive writing in improving the quality of life in women with breast cancer and lymphedema.

NCT ID: NCT00677430 Completed - Breast Cancer Clinical Trials

Quantitative Analysis of Outcomes in Breast Reconstruction

Start date: May 2008
Phase:
Study type: Observational

The first objective of this study is to assess the accuracy of digital image-processing techniques to provide measurements of human breast physical dimensions. The ultimate usefulness of these techniques is to develop quantitative outcome measures of the visual appearance of breast after local treatments for breast cancer. These measures will be used to improve clinical outcomes from multimodality therapy that includes surgery and radiotherapy and form the basis for the future development of patient decision making aids. The second objective is to evaluate the relationship between patient reported body image outcomes and measurement of human breast physical dimensions for patients with breast cancer.

NCT ID: NCT00676793 Completed - Breast Cancer Clinical Trials

A Study of the Effect of Polyphenon E (Green Tea Extract) on Breast Cancer Progression

Start date: May 2004
Phase: Phase 2
Study type: Interventional

To see if an extract of green tea can affect certain markers of breast cancer and breast cancer progression in women with a recent biopsy positive for cancer and who are scheduled for surgery.