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Breast Neoplasms clinical trials

View clinical trials related to Breast Neoplasms.

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NCT ID: NCT01656538 Completed - Clinical trials for Metastatic Breast Cancer

A Study of Reolysin For Patients With Advanced/Metastatic Breast Cancer

Start date: February 20, 2013
Phase: Phase 2
Study type: Interventional

Researchers doing this study want to evaluate the side effects of Reolysin when given together with paclitaxel. As these drugs have not been given together before, 6-9 patients will be treated with paclitaxel plus reolysin to ensure that side effects are tolerable.

NCT ID: NCT01654185 Completed - Clinical trials for Metastatic Breast Cancer

Dimethyldiguanide Combined With Aromatase Inhibitor (AI) in Metastatic Breast Cancer

Start date: July 2012
Phase: Phase 2
Study type: Interventional

The addition of dimethyldiguanide might increase the efficacy of AI treatment in metastatic breast cancer.

NCT ID: NCT01653574 Completed - Breast Neoplasms Clinical Trials

A Study of Famitinib Malate in HER2-negative Metastatic Breast Cancer

Start date: May 2012
Phase: Phase 2
Study type: Interventional

The hypothesis of this clinical research study is to discover if the study drug Famitinib Malate can shrink or slow the growth of pretreated HER2-negative metastatic breast cancer.

NCT ID: NCT01653561 Completed - Breast Neoplasms Clinical Trials

A Study of Apatinib in Non-triple-negative Metastatic Breast Cancer

Start date: November 2011
Phase: Phase 2
Study type: Interventional

The hypothesis of this clinical research study is to discover if the study drug apatinib can shrink or slow the growth of pretreated non-triple-negative metastatic breast cancer.

NCT ID: NCT01650506 Completed - Breast Cancer Clinical Trials

Study of Erlotinib and Metformin in Triple Negative Breast Cancer

Start date: July 2012
Phase: Phase 1
Study type: Interventional

Extended phase 1 trial of combined metformin and erlotinib in advanced triple negative breast cancer patients. The goals of the study are to establish the maximum tolerated combined dosing of erlotinib and metformin as well as deciding if there is a potential clinical utility of the combination in treating patients with triple negative breast cancer.

NCT ID: NCT01649271 Completed - Breast Neoplasms Clinical Trials

Phase I Trial of Afatinib and Trastuzumab in HER2 Overexpressing Cancer.

Start date: July 23, 2012
Phase: Phase 1
Study type: Interventional

The aim of the study is to determine the Maximum Tolerated Dose (MTD) of afatinib in combination with 3-weekly trastuzumab in HER2 overexpressing cancer and to assess the efficacy of afatinib given at the MTD dosage, with 3-weekly trastuzumab in HER2 overexpressing metastatic breast cancer.

NCT ID: NCT01648322 Completed - Breast Cancer Clinical Trials

Dose-Finding Trial of F-627 in Women With Breast Cancer Receiving Myelotoxic Chemotherapy

Start date: June 2012
Phase: Phase 2
Study type: Interventional

This is a randomized open label dose finding study to evaluate the efficacy and safety of F-627 on women with Stage I-IV breast cancer receiving chemotherapy treatment.

NCT ID: NCT01647607 Completed - Breast Cancer Clinical Trials

Young and Strong: An Education and Supportive Care Intervention Study for Young Women With Breast Cancer

Y&S
Start date: June 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to address gaps in care of young women with breast cancer by determining whether educational interventions focusing on issues unique to young women with breast cancer and healthy lifestyles for women with breast cancer help to improve care of young breast cancer patients. The investigators believe that if addressed early in a young woman's care, concerns related to fertility, body image, sexual dysfunction, and physical activity will improve the satisfaction with care and quality of life of this vulnerable population. The research will be conducted by exporting refined, previously piloted educational interventions to 14 academic sites and 40 community medical clinics. The investigators will compare how interaction with each intervention affects patients' quality of life and satisfaction with quality of care.

NCT ID: NCT01646346 Completed - Breast Cancer Clinical Trials

4D Image-Guided Partial Breast Radiation in Stage 0 and l Breast Cancer

Start date: January 10, 2012
Phase: N/A
Study type: Interventional

The Purpose of this study is to evaluate the feasibility of using image guidance and four-dimensional computed tomography to reduce the volume of non target breast tissue that is treated with accelerated partial breast irradiation via the external beam technique.

NCT ID: NCT01645839 Completed - Breast Cancer Clinical Trials

Interest of Intrathecal Chemotherapy With Liposomal Cytarabine (DepoCyte®) in Meningeal Metastasis of Breast Cancer

DEPOSEIN
Start date: August 30, 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the impact of Depocyte® IT combined with the systemic standard treatment in terms of clinical and/or radiological neuromeningeal progression free survival (SSPN)