Breast Cancer Clinical Trial
Official title:
A Phase 1 Open-Label, First-in-Human Trial of Oral MBQ-167 as Single Agent in Participants With Advanced Breast Cancer
A Phase 1, open-label, dose-escalation clinical trial of MBQ-167 in participants with advanced Breast Cancer for whom Standard of Care (SOC) has failed or has proven intolerable.
The main questions this clinical trial aims to answer are: - What, if any, are the side effects of different dose levels in humans? - What is the maximum tolerated dose? - How does the human body process the drug? - Does the drug slow, stop or eliminate cancer in human participants? Participants will be asked to: - provide informed consent - be evaluated by physicians and provide laboratory specimens to determine if eligible - take MBQ-167 orally twice a day for at least 21 days - may continue dosing, if safe to do so, until not effective or other decision to stop is made - participate in multiple visits that include additional evaluations, laboratory tests and diary review until after stopping the investigational drug ;
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