Pyrotinib After Trastuzumab-based Adjuvant Therapy in Patients With

Status Recruiting

Clinical Trial Summary

This trial is a multicenter, open-label, phase II trial conducted at 23 centers in China. High-risk HER2 positive patients receive pyrotinib 400mg/day for one year or half year for extented adjuvant therapy.

Clinical Trial Description

Patients must meet one of the following criteria: N stage ≥1; T stage ≥2; did not achieve pathological complete response (pCR) after neoadjuvant therapy; had pCR after neoadjuvant therapy but with tumor size ≥ 5cm or N stage ≥2; or tumor size less than 2cm but with high Ki67; histologic grade 3 or with lymph node micrometastasis. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05880927
Study type	Interventional
Source	Taizhou Hospital
Contact	Feilin Cao, Master
Phone	13806562998
Email	drcfl@126.com
Status	Recruiting
Phase	Phase 2
Start date	January 1, 2019
Completion date	December 31, 2025

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Pyrotinib After Trastuzumab-based Adjuvant Therapy in Patients With HER2-positive Breast Cancer

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms