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Feasibility of Exosome Analysis in Cerebrospinal Fluid During the Diagnostic Workup of Metastatic Meningitis (Exo-LCR) — Exo-LCR  

Breast Cancer Clinical Trial

Official title:
Feasibility of Exosome Analysis in Cerebrospinal Fluid During the Diagnostic Workup of Metastatic Meningitis From Breast Cancer

Clinical Trial Summary

The investigators are interested in one of the most frequent tumor types causing leptomeningeal metastasis in order to investigate whether a profile can be established by a high-throughput clinical proteomic approach. All the data acquired will allow a tailored and promising approach to improve the knowledge of metastatic tumor meningitis.

Clinical Trial Description

The primary objective is to describe on an exploratory basis the association between the type of proteomic profile from cerebrospinal fluid (CSF) microvesicles (from unsupervised bioinformatics analysis) and CSF cytology analysis (positive, negative, equivocal) in breast cancer patients with suspected leptomeningeal metastases, on initial CSF samples (hereafter referred to as initial proteomic profile and initial cytology). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05286684
Study type Interventional
Source Centre Oscar Lambret
Contact Julien Thery
Phone +33320295918
Email promotion@o-lambret.fr
Status Recruiting
Phase N/A
Start date January 4, 2023
Completion date December 2026
View Details
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