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Dissecting the Pathways of Therapy Resistance in Early Breast Cancer — MINDACTRelapse  

Breast Cancer Clinical Trial

Official title:
Dissecting the Pathways of Therapy Resistance in Early Breast Cancer: A Sub-study of the EORTC 10041/BIG 3-04 MINDACT Study

Clinical Trial Summary

Within the 1st step MINDACT patients who have already relapsed will be asked to participate. For these patients a biopsy of the metastasis should have been taken. A molecular analysis of the stored primary tumor sample and of the metastatic sample, using new technologies, will be performed, and the characteristics of both samples will be compared. Within the 2nd step a prospective collection of the metastasis samples will be implemented and analysis of biological material from relapsing MINDACT patients is foreseen. This process will provide insights on the biology of breast cancer and allow us to better understand mechanisms of resistance to therapies, contributing to overcoming this important problem.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04995575
Study type Observational
Source European Organisation for Research and Treatment of Cancer - EORTC
Contact
Status Terminated
Phase
Start date July 8, 2020
Completion date October 23, 2023
View Details
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