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Pilot Study of the Predictive Value of TREM1 Expression and Activation in Inflammation and Radio-induced Mammary Fibrosis — TREM-1  

Breast Cancer Clinical Trial

Official title:
Pilot Study of the Predictive Value of TREM1 Expression and Activation in Inflammation and Radio-induced Mammary Fibrosis

Clinical Trial Summary

Breast cancer is the most common cancer in the world. Half of patients with such cancer are treated with radiation therapy. Some patients will develop cutaneous or subcutaneous fibrosis, more or less bothersome. Several studies have shown a correlation between an inflammatory reaction and a protein, called TREM-1. But to date, no link has been proven between TREM-1 and inflammation / fibrosis in the phenomena of fibrosis induced by radiotherapy in patients with breast cancer. Our study aims to understand the involvement of this TREM-1 protein in the development of fibrosis or radio-epidermis in patients with breast cancer.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04948840
Study type Interventional
Source Centre Francois Baclesse, Luxembourg
Contact Guillaume VOGIN, MD PhD
Phone 00352-2655661
Email guillaume.vogin@baclesse.lu
Status Recruiting
Phase N/A
Start date April 1, 2022
Completion date December 31, 2024
View Details
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