A Study of PY314 in Subjects With Advanced Solid Tumors

Status Terminated

Clinical Trial Summary

This is an open-label, multicenter, first in human, Phase 1a/1b study of PY314 in subjects with locally advanced (unresectable) and/or metastatic solid tumors that are refractory or relapsed to standard of care (including pembrolizumab, if approved for that indication).

Clinical Trial Description

Part A: Dose escalation of PY314 alone and in combination with pembrolizumab in a standard 3+3 design Part B: Dose expansion of one or more dose levels of PY314 administered alone and in combination with pembrolizumab for predefined tumor histology ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04691375
Study type	Interventional
Source	Ikena Oncology
Contact
Status	Terminated
Phase	Phase 1
Start date	October 29, 2020
Completion date	September 22, 2023

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