Breast Cancer Clinical Trial
Official title:
Clinical Study of Metabolomics-based Approach Explore Biomarkers for Metastatic Breast Cancer
RATIONALE: Studying samples of plasm by metabolomics-based approach from women with
metastasis breast cancer may help doctors understand the biomarker of visceral metastasis.
PURPOSE: This clinical trial is studying the biomarker of visceral metastasis by metabolomics
approach in metastasis breast cancer undergoing treatment.
Imaging evaluation of the effect of chemotherapy on patients with visceral metastases from
breast cancer, metabolomics was used to analyze the changes of metabolites in plasma, and to
find biomarkers that could reflect visceral metastasis and treatment effects. The purpose is
to help clinicians predict whether patients have potential visceral metastases, evaluate the
effects of visceral metastasis treatment, and reflect the patient's prognosis.
Patients with visceral metastases on imaging examinations received chemotherapy as planned,
and blood samples were collected from patients before and during imaging assessments.
Analysis of metabolites in plasma using ultra high performance liquid chromatography. Patient
information were collected through medical record, including race, age, height and body mass
index, menarche age, menstrual status, menopausal age (if applicable), tobacco and alcohol
history, motherhood history, family history, etc.
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