Breast Cancer Clinical Trial
Official title:
Clinical Study of Nab-paclitaxel Plus Carboplatin Versus Nab-paclitaxel Plus Epirubicin in the Neoadjuvant Therapy for Breast Cancer
This is a multicenter, open, randomized, comparison study. Triple-negative breast cancer
(TNBC) is a term applied to breast cancer cases that have <1% expression of the estrogen
receptor (ER) and the progesterone receptor (PR) and do not over express HER2.
Neoadjuvant therapy is often used to reduce the size of tumors, especially in locally
advanced tumors. The purpose of this therapy is to make part of patients operable and to
facilitate breast-conserving surgery.
The purpose of this study is to assess the efficacy and safety of the following two
proposals: nab-paclitaxel plus carboplatin versus nab-paclitaxel plus epirubicin, in order to
provide support for rational clinical application.
The total number of patients to be included in this study is 520 patients.
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