The Jewels in Our Genes Study - an African American Family Study of Breast Cancer

Breast Cancer Clinical Trial

Official title:

Search for Novel Breast Cancer Susceptibility Genes in Pedigrees of African Ancestry

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01380925
• Other study ID #: KG090937
• Status: Completed
• Phase: N/A
• First received: June 22, 2011
• Last updated: May 10, 2016
• Start date: October 2010
• Est. completion date: August 2012

Study information

• Verified date: May 2016
• Source: University at Buffalo
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

The research team is studying why some African American families have multiple cases of breast cancer.

This study will help to better understand if there are undiscovered genes unique to African Americans that may predict early breast cancer risk.

Breast cancer survivors AND their relatives who are also breast cancer survivors are being recruited to the study.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 330
• Est. completion date: August 2012
• Est. primary completion date: August 2012
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 18 Years to 100 Years

Eligibility

Inclusion Criteria:

• Black/African American

• Ever diagnosed with breast cancer

• Have at least one living blood relative ever diagnosed with breast cancer, who is also willing to participate

• Live in the U.S.

Exclusion Criteria:

• Tested positive for BRCA mutations

Study Design

Observational Model: Family-Based, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Breast Cancer
• Breast Neoplasms

Locations

Country	Name	City	State
United States	University at Buffalo	Buffalo	New York

Sponsors (2)

Lead Sponsor	Collaborator
University at Buffalo	Susan G. Komen Breast Cancer Foundation

Country where clinical trial is conducted

United States, 

References & Publications (1)

Ochs-Balcom HM, Sun X, Chen Y, Barnholtz-Sloan J, Erwin DO, Jandorf L, Sucheston-Campbell L, Elston RC. Putative linkage signals identified for breast cancer in African American families. Cancer Epidemiol Biomarkers Prev. 2015 Feb;24(2):442-7. doi: 10.115 — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	breast cancer