Breast Cancer Clinical Trial
Official title:
Pilot Study to Test Uniformity of Transdermal Drug Delivery to the Breast Using Diclofenac Epolamine as a Model
The purpose of this study is to look for ways to improve breast cancer treatment by giving
breast cancer drugs through the skin of the breast.
The drug used in this study is a diclofenac epolamine patch and is a nonsteroid
anti-inflammatory pain reliever. The drug amount that gathers in the breast, after
application of a patch to the skin of the breast, will be measured and compared to the amount
that is found in the breast when the patch is applied to the skin of the belly.
This is a randomized study where participants in group 1 will apply the diclofenac epolamine patch to the breast and participants in group 2 will apply the same drug to her abdomen. Participants are instructed to apply a new patch every 12 hours for 3 days. Total participation in this study will be for three days, ending on the day of surgery. On the day of surgery, participants will have blood drawn to measure the level of diclofenac epolamine in the body, and the final patch will be removed. ;
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