Breast Cancer Clinical Trial
Official title:
The Use of Molecular Breast Imaging in the Evaluation of Tumor Response to Neoadjuvant Therapy in Women With Breast Cancer - A Pilot Study
In patients with breast cancer who undergo neoadjuvant chemotherapy or neoadjuvant hormone therapy molecular breast imaging (MBI) is an accurate test for assessing response rate to neoadjuvant therapy.
The investigators propose to evaluate Molecular Breast Imaging in patients undergoing
neoadjuvant therapy for breast cancer with the aims to document that 1) the change in uptake
of 99mTc-sestamibi prior to initiation of neoadjuvant therapy, after 3-5 weeks of
neoadjuvant therapy and at completion of neoadjuvant therapy prior to breast cancer surgery
will be a reflection of the tumor response to neoadjuvant therapy.
2) Tumor response at 3-5 weeks of neoadjuvant therapy is predictive of tumor response at
completions of neoadjuvant therapy.
3) Post-neoadjuvant tumor size as determined by MBI corresponds to size found at surgery.
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Observational Model: Case-Only, Time Perspective: Prospective
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