TOBI to Monitor Response to Neoadjuvant Therapy in Breast Cancer

Status Completed

Clinical Trial Summary

The purpose of this research study is to see if Near-Infrared Tomographic Optical Breast Imaging (TOBI) scans can help monitor breast tumor response during treatment for breast cancer. The images created by the TOBI scan show changes in blood blow and oxygen levels in breast tissue.

Clinical Trial Description

- Participants will have a TOBI scan prior to starting their cancer treatment and again on day 8 after their first treatment. Participants will also be asked if they would volunteer to undergoing one or more additional TOBI scans on days 2-7 after they begin cancer treatment. These additional scans are optional. Participants will also have a scan on the first day of each treatment cycle.

- TOBI scans will be performed at the Gillette Center for Breast Cancer at the Massachusetts General Hospital.

- For the scan, each breast is placed between 2 plastic plates in order to spread the tissue apart, similar to the procedure for a mammogram. The TOBI scanner is attached to these plates. We will apply mild pressure to compress the breast and the breast will be scanned using light waves. Each scan will take about 3 minutes. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00783757
Study type	Interventional
Source	Massachusetts General Hospital
Contact
Status	Completed
Phase	N/A
Start date	August 2008
Completion date	June 2017

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