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Clinical Trial Summary

Imaging procedures such as 1-(2-[18F]FLUOROETHYL)-L-Tryptophan PET/CT in patients with cancers may help doctors assess a patient's response to treatment and help plan the best treatment in the future. The purpose is to see if there can be a better differentiation of tumor and non-tumor tissue where the tumor tissue has a higher uptake of Tryptophan.


Clinical Trial Description

In this research study, we will compare the uptake of the tracer on F-Tryp PET/CT in patients with cancers; specifically, to evaluate whether the tumors show increased tracer uptake as compared to non-tumor tissues, using F-Tryp PET/CT. Additionally, we will evaluate the biodistribution (i.e. track where the tracer has traveled in the body) and radiation dosimetry (i.e., absorbed dose of tracer in tissue). These changes may be compared with results of the physical examination and scans (CT and MRI or standard clinical PET) that are done as part of routine clinical care or as part of other studies. Pictures (images) from the PET scan will be made showing the distribution throughout the body of substances containing a small amount of radioactive material. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05556473
Study type Interventional
Source Barbara Ann Karmanos Cancer Institute
Contact Csaba Juhasz, M.D., Ph.D
Phone 313-966-5136
Email csaba.juhasz@wayne.edu
Status Recruiting
Phase Phase 1
Start date September 29, 2022
Completion date December 31, 2024

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