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Brain Tumor clinical trials

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NCT ID: NCT00831324 Recruiting - Brain Tumor Clinical Trials

Everolimus in Treating Patients With Recurrent or Progressive Low-Grade Glioma

Start date: January 2009
Phase: Phase 2
Study type: Interventional

RATIONALE: Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. PURPOSE: This phase II trial is studying how well everolimus works in treating patients with recurrent or progressive low-grade glioma.

NCT ID: NCT00798811 Active, not recruiting - Brain Tumor Clinical Trials

High-dose Chemotherapy With Autologous Stem Cell Rescue in Pediatric High-risk Brain Tumors

Start date: September 2005
Phase: Phase 2
Study type: Interventional

- Study No.: KSPNO-S-081 Reduced-dose Craniospinal Radiotherapy Followed by High-dose Chemotherapy and Autologous Stem Cell Rescue in Children with Newly Diagnosed High-risk Brain Tumor - Study No.: KSPNO-S-082 High-dose Chemotherapy and Autologous Stem Cell Rescue in Infants and Young Children with Newly Diagnosed High-risk Brain Tumor To Avoid or Reduce Craniospinal Radiation - Study No.: KSPNO-S-083 High-dose Chemotherapy and Autologous Stem Cell Rescue in Children with Recurrent Brain Tumor or Non-germinomatous Germ Cell Tumor with Inadequate Response to Conventional Treatment

NCT ID: NCT00777686 Completed - Glioblastoma Clinical Trials

Measuring Non-Enhancing Glioblastoma Progression

Start date: August 2008
Phase: N/A
Study type: Observational

The goal of this clinical research study is to learn if magnetic resonance imaging with magnetic resonance spectroscopy ("MRI/MRS" scanning) can measure any extra growth in the tumor that does not show up on regular MRI images. This study procedure will be performed on patients with recurrent glioblastoma who are either being treated with chemotherapy that blocks blood vessel growth, or will soon begin this type of chemotherapy.

NCT ID: NCT00775320 Terminated - Brain Tumor Clinical Trials

Assessment of Suspected Intracranial Malignancy Using 3'-Deoxy-3'18 F-flourothymidine PET

Start date: October 2008
Phase:
Study type: Observational

The primary objective of this study is to detect and quantify tumor cells of high grade malignant gliomas and metastatic brain lesions both before and after initial surgical resection in a cohort of newly diagnosed patients.

NCT ID: NCT00763750 Completed - Brain Tumor Clinical Trials

PPX, Temozolomide, and Concurrent Radiation for Newly Diagnosed Brain Tumors

Start date: October 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the antitumor activity of PPX in combination with temozolomide and radiation for patients with newly diagnosed brain tumors.

NCT ID: NCT00760409 Completed - Brain Tumor Clinical Trials

Differentiating Recurrent Brain Tumor Versus Radiation Injury Using MRI

Start date: September 2008
Phase: N/A
Study type: Observational

The purpose of this study is to determine if certain MRI imaging sequences (pictures) are more helpful to the physicians in determining if a brain tumor has recurred or if the person has radiation injury following their treatment.

NCT ID: NCT00748774 Completed - Brain Tumor Clinical Trials

Brain Tumor Patient-Caregiver Congruence, MD Anderson Symptom Inventory-Brain Tumor Module (MDASI-BT)

Start date: May 2008
Phase: N/A
Study type: Observational

The goal of this study is to compare patient ratings of how severe their own symptoms may be, with their caregivers' ratings of how severe they think the patients' symptoms may be. This will be compared using a questionnaire that is given to patients with brain tumors and their caregivers. Researchers will also study any effects that these patients' neurocognitive function may have on these patients' and their caregivers' ratings of how severe the brain cancer symptoms may be.

NCT ID: NCT00747253 Completed - Clinical trials for Glioblastoma Multiforme

Monteris AutoLITTâ„¢ FIM Safety Trial for Recurrent/Progressive Brain Tumors

Start date: August 2008
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to evaluate the safety and performance of the AutoLITT system for the treatment of recurrent/progressive glioblastoma multiforme tumors (GBM).

NCT ID: NCT00720837 Terminated - Brain Tumor Clinical Trials

Magnetic Resonance Temperature Imaging & Imaging-Guided Laser Induced Thermal Therapy for Treatment of Metastatic Brain Tumors

Start date: July 2008
Phase: N/A
Study type: Interventional

The goal of this clinical research study is to learn about a new therapy device called the Visualase® Thermal Therapy System (a device that uses a laser to kill tumor cells and is guided using magnetic resonance thermal imaging [MRTI]). The Visualase® Thermal Therapy System is used to treat metastatic brain tumors. Researchers want to find out if it is possible to use this new device in patients with metastatic brain tumor(s), each measuring 3 centimeters (cm) or smaller. The safety of the device will also be studied.

NCT ID: NCT00716976 Completed - Ovarian Cancer Clinical Trials

Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy

Start date: June 23, 2008
Phase: Phase 3
Study type: Interventional

RATIONALE: Sodium thiosulfate may reduce or prevent hearing loss in young patients receiving cisplatin for cancer. It is not yet known whether sodium thiosulfate is more effective than no additional treatment in preventing hearing loss. PURPOSE: This randomized phase III trial is studying sodium thiosulfate to see how well it works in preventing hearing loss in young patients receiving cisplatin for newly diagnosed germ cell tumor, hepatoblastoma, medulloblastoma, neuroblastoma, osteosarcoma, or other malignancy.