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Brain Injuries clinical trials

View clinical trials related to Brain Injuries.

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NCT ID: NCT04836481 Completed - Clinical trials for Traumatic Brain Injury

A Pharmacokinetic Analysis of Levetiracetam Prophylaxis in Critically Ill Patients With Severe Traumatic Brain Injury

Start date: January 1, 2021
Phase:
Study type: Observational

This study aims is to describe the pharmacokinetic properties of levetiracetam through measurement of serum concentrations in critically ill, severe traumatic brain injury patients.

NCT ID: NCT04835272 Not yet recruiting - Clinical trials for Acquired Brain Injury

Comparison of the Decannulation Protocol With Suctioning and Capping in Severe Acquired Brain Injury Patients

Start date: November 1, 2021
Phase: N/A
Study type: Interventional

Single-center randomized trail focused on tracheostomized patients with severe acquired brain injury , comparing two different decannulation protocols: 1. an assessment of readiness for decannulation that was based on suctioning frequency 2. an assessment that was based on tracheostomy capping

NCT ID: NCT04833543 Recruiting - Brain Injuries Clinical Trials

Verticalization Robotic Exoskeleton DoC

Start date: April 21, 2021
Phase: N/A
Study type: Interventional

Mobilization, specifically verticalization, has been shown to play a role in enhancing consciousness. Vestibular stimulation has the potential to influence the neural substrate of consciousness, but this modality has not been thoroughly explored. The primary aim of this study is to compare the influence of verticalization with and without vestibular input on level of consciousness in patients experiencing disorders of consciousness (DoC).

NCT ID: NCT04833218 Active, not recruiting - Clinical trials for Traumatic Brain Injury

Propranolol Versus Propranolol and Clonidine in Sympathetic Hyperactivity After Moderate Traumatic Brain Injury

Start date: January 31, 2020
Phase: Early Phase 1
Study type: Interventional

evaluation of the effect of Propranolol versus propranolol and clonidine on decreasing sympathetic hyperactivity after moderate traumatic brain injury

NCT ID: NCT04826068 Completed - Clinical trials for Traumatic Brain Injury

Emotional Processing Intervention for Children With TBI

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

Investigating an emotional processing program, that is modified for use with children, is effective for children with a traumatic brain injury (TBI).

NCT ID: NCT04823507 Completed - Clinical trials for Mild Traumatic Brain Injury

Photobiomodulation for Concussions: the Use of the ImPACT® Test as an Assessment Tool

Start date: March 26, 2021
Phase:
Study type: Observational

Brain photobiomodulation (PBM) therapy is an innovative modality for the stimulation of neural activity in order to improve brain function and is currently under investigation as a treatment for several diverse neurological disorders. Our emphasis on this study is to review the use of PBM as a treatment modality for concussions and the use of ImPACT® (Immediate Post-Concussion Assessment and Cognitive Testing) test to assess improvement in cognition and symptomatology in patients with post-concussion syndrome (PCS) treated with PBM.

NCT ID: NCT04822311 Completed - Depression Clinical Trials

Evaluating the Impact of Focused Muscle Contraction Therapy in Retire APF Players

GH-APF
Start date: October 24, 2019
Phase: N/A
Study type: Interventional

This study will investigate the effects of an exercise intervention on retired American professional football (APF) players. A total of 20 retired APF players (≥ 18 years of age), who suffer from chronic pain, will be enrolled. The study duration for each participants will be 18 months. Enrolled participants will perform a 18 months exercise intervention which involves 90 exercise rehabilitation training visits. In addition, participants will also be tested on various measures of health and function both at baseline (prior to intervention), at 6 months, 12 months, and 18 months (post intervention). All testing and result interpretation will be performed by trained research personnel. Participants are not University of Illinois at Chicago (UIC) participants; however, study testing visits will occur at UIC. All exercise intervention training visits will occur at Gh Fitlab.

NCT ID: NCT04820881 Recruiting - Clinical trials for Neurodegenerative Diseases

Cerebrovascular Reactivity and Oxygen Metabolism as Markers of Neurodegeneration After Traumatic Brain Injury

Start date: October 1, 2021
Phase:
Study type: Observational

This grant award entitled, "Cerebrovascular Reactivity and Oxygen Metabolism as Markers for Neurodegeneration after Traumatic Brain Injury" (hereafter, "Neurovascular Study"), aims to determine if neurovascular contributors to neurodegeneration can serve as markers of the emergence or progression of degenerative processes after traumatic brain injury in middle-aged and older adults.

NCT ID: NCT04820634 Recruiting - Clinical trials for Traumatic Brain Injury

Using Virtual Reality to Improve Job Reentry in Adults With TBI

Start date: December 12, 2019
Phase: N/A
Study type: Interventional

The purpose of this research is to investigate the effectiveness of virtual reality (VR) to improve job reentry skills in individuals with TBI.

NCT ID: NCT04819984 Not yet recruiting - Acute Brain Injury Clinical Trials

Impact of Continuous Monitoring of PtC02 on Ventilatory Weaning in Neuro-injured Patients

CO2MBAWA
Start date: April 1, 2021
Phase: N/A
Study type: Interventional

The investigators propose to study the value of non invasive continuous transcutaneous PtC02 monitoring for ventilatory withdrawal guidance in neuro-injured patients and to predict the risk of extubation failure in this category of patients, particularly at risk of re-intubation.