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Bone Tumor clinical trials

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NCT ID: NCT05075889 Completed - Bone Tumor Clinical Trials

Utility of ICG in Benign Bone Tumors

Start date: November 11, 2021
Phase: Early Phase 1
Study type: Interventional

Patients with a biopsy-proven benign bone tumor for which standard of care is intralesional operative management will receive a weight-appropriate IV dose of indocyanine green (ICG, FDA-approved) the day prior to surgery during their standard pre-operative clinic visit. On the day of surgery, fluorescence images will be obtained using a non-invasive fluorescence camera.

NCT ID: NCT04955522 Completed - Bone Tumor Clinical Trials

Multimodal Imaging Analysis of Spinal Tumors

Start date: December 1, 2019
Phase:
Study type: Observational

In this study, we retrospectively analyzed the imaging data of spinal tumors to find out more imaging features of spinal tumors, in order to provide more accurate reference for the diagnosis of spinal tumors.

NCT ID: NCT04798326 Completed - Bone Tumor Clinical Trials

Comparing of the Pharmacokinetic, Pharmacodynamic, Safety and Immunogenicity of MW032 and Xgeva® in Healthy Adults

MW032
Start date: June 25, 2019
Phase: Phase 1
Study type: Interventional

A randomized, double-blind and parallel group study to compare the pharmacokinetic, safety and pharmacodynamic of MW032 and Xgeva® in healthy adults.

NCT ID: NCT04755140 Recruiting - Heart Diseases Clinical Trials

Endoprosthesis Metal Toxicity Study

Start date: March 19, 2021
Phase:
Study type: Observational

The purpose of this research is to investigate whether patients who previously had endoprosthesis surgery experience memory, thinking, or heart problems. It will also help determine how often these problems occur.

NCT ID: NCT04178044 Recruiting - Bone Tumor Clinical Trials

Phase Ⅰ Clinical Study Protocol of GB223 Monoclonal Antibody Injection

Start date: November 16, 2018
Phase: Phase 1
Study type: Interventional

The primary objective of this study is to evaluate the safety, tolerability and pharmacokinetic (PK) profiles of single dose of GB223 in healthy subjects; the secondary objective is to evaluate the immunogenicity and pharmacodynamic (PD) profiles of single dose of GB223 in healthy subjects.

NCT ID: NCT04104750 Active, not recruiting - Quality of Life Clinical Trials

The Assessment of Fatigue and Quality of Life in Patients With Bone Tumor,

Fatigue-ONCO
Start date: July 26, 2019
Phase:
Study type: Observational [Patient Registry]

The aim of the present observational study is to evaluate and describe the evolution over time of the fatigue and the quality of life of patients with bone tumor, in Rizzoli Orthopedic Institute, Chemotherapy ward, during the chemotherapy treatment and in the first phase of follow-up and to identify possible prognostic factors. Such knowledge is a necessary precondition for identifying patients and the periods most at risk due to the onset of fatigue, so as to be able to hypothesize adequate containment strategies.

NCT ID: NCT03427632 Not yet recruiting - Bone Tumor Clinical Trials

Role of Percutaneous Vertebroplasty in Treatment of Vertebral Tumors

PVP
Start date: March 1, 2018
Phase: N/A
Study type: Observational [Patient Registry]

Percutaneous vertebroplasty is a new technique to strengthen bone and reduce pain for patients with vertebral tumors

NCT ID: NCT03389724 Completed - Cardiotoxicity Clinical Trials

Prevention of Chemotherapy Induced Cardiotoxicity in Children With Bone Tumors and Acute Myeloid Leukemia

Start date: November 14, 2017
Phase: Phase 3
Study type: Interventional

Prevention and early detection of chemotherapy-induced cardiotoxicity in children with bone tumors and Acute Myeloid Leukemia by giving capoten

NCT ID: NCT02862288 Completed - Bone Tumor Clinical Trials

Preliminary Study of Microwave Tumoral Ablation Performances for the Treatment of Pulmonary, Renal and Bone Neoplasia.

TherMO
Start date: September 2012
Phase: Phase 1/Phase 2
Study type: Interventional

The aims of this work were to assess the feasibility, efficacy, short-term outcome and safety of microwave ablation in the treatment of malignant bone, lung and renal tumors.

NCT ID: NCT02398058 Completed - Soft Tissue Sarcoma Clinical Trials

Trabectedin Plus Olaparib in Metastatic or Advanced Sarcomas (TOMAS)

TOMAS
Start date: July 20, 2014
Phase: Phase 1
Study type: Interventional

This is a Phase 1b, multi-site, open-label, non-randomized clinical trial evaluating the safety, tolerability, and pharmacokinetics of escalating doses of olaparib and trabectedin in patients with unresectable advanced/metastatic sarcomas. Patients will continue to be treated on this combination regimen in the absence of disease progression, intolerable toxicity or patient's decision.