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Bone Loss clinical trials

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NCT ID: NCT06017596 Completed - Bone Loss Clinical Trials

CAD-CAM PEEK Framework for All-on-4 Implants

Start date: February 23, 2021
Phase: N/A
Study type: Interventional

This study was conducted to evaluate the clinical peri-implant soft tissue changes during the first year after occlusal loading and the ridge base relation after 3 years for mandibular computer-aided design and computer-aided manufacturing (CAD/CAM) screw-retained implant-supported hybrid prosthesis of polyetheretherketone (PEEK) framework utilized with All-on-Four treatment concept.

NCT ID: NCT06017115 Active, not recruiting - Bone Loss Clinical Trials

Evaluation of Using Different Screwed Abutment Height

Start date: July 1, 2017
Phase: N/A
Study type: Interventional

A prospective randomized controlled clinical trial will be conducted. Study groups will be assigned as described above. The patients will be randomly divided into two groups in order to study the influence of prosthetic screw abutment in marginal bone loss (MBL) around Bone Level Tapered implants (BLT® Roxolid® SLActive® guided implants, Straumann Dental Implant System, Institut Straumann AG, Basel, Switzerland).

NCT ID: NCT05961371 Recruiting - Osteoporosis Clinical Trials

Strength Training for Osteoporosis Prevention During Early Menopause

STOP-EM
Start date: November 1, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical pilot trial is to learn about the feasibility of a high-intensity resistance training intervention in peri- and early menopausal females. The main question it aims to answer are: -Is a 9-month resistance training intervention feasible (e.g., recruitment rates, protocol adherence, attrition) Secondary aims include examining changes in bone health, muscle strength, and menopausal symptoms. Participants will participate in a 9-month progressive, supervised, resistance training intervention. Researchers will compare secondary outcomes between the exercise group and a wait-list control group.

NCT ID: NCT05960136 Completed - Bone Loss Clinical Trials

Impact of COVID-19 on Sinus Augmentation Surgery

Start date: March 30, 2023
Phase: N/A
Study type: Interventional

The risk of Schneiderian membrane perforation and the postoperative complications of the sinus floor elevation surgery were evaluated for patients with and without history of COVID-19 infection.

NCT ID: NCT05957926 Not yet recruiting - Bone Loss Clinical Trials

Hyaluronic Acid +Hydroxyapatite Vs Hydroxyapatite in Bone Regeneration

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

Evaluation of the effect of hyaluronic acid with hydroxyapatite versus hydroxyapatite alone on bone regeneration following enucleation of mandibular odontogenic cyst.

NCT ID: NCT05939531 Recruiting - Stroke Clinical Trials

Multi-domain Intervention Program for Post-stroke Bone Health in Older Adults (BOUNCE)

BOUNCE
Start date: March 1, 2023
Phase: N/A
Study type: Interventional

The goal of this feasibility randomized controlled trial is to assess the feasibility and compare the changes in bone mineral density before and after the intervention in post-stroke older adults. The main question[s] it aims to answer are: - What are the baseline sociodemographic and bone health characteristics of post-stroke older adults in this study? - Is it feasible to undertake a larger RCT to assess the effectiveness and implementation of BOUNCE program? - Is there a difference in bone loss between groups? - Is there a difference in bone turnover markers at baseline and at six months? - Is there a difference in the incidence of falls and fragility fractures between groups? - How receptive are post-stroke patients/carers to the use of food/exercise diary? - What are the perceived motivators and barriers to implementation of BOUNCE program within real clinical settings among healthcare professionals, participants and carers? - What is the experience of healthcare professionals, participants and carers undergoing BOUNCE program? Participants will be divided into two groups: 1. Standard care 2. Intervention group (BOUNCE Program) Researchers will compare both groups to see any changes in the bone mineral density and bone turnover markers before and after the intervention.

NCT ID: NCT05918029 Recruiting - Clinical trials for Chronic Kidney Diseases

Bone in CKD Alkali Response (BICARb Pilot Trial)

BICARb
Start date: June 2024
Phase: Phase 2/Phase 3
Study type: Interventional

The goal of this clinical trial is to test whether potassium citrate improves skeletal health in adults and children with chronic kidney disease. The main questions it aims to answer are: - To evaluate effects of potassium citrate treatment on bone quality and strength. - To evaluate mechanism(s) underlying the effects of potassium citrate on skeletal health. Participants will be asked to: - provide blood, urine and answer questions about health and diet three times during an 8 months period - undergo advanced bone imaging with high resolution-peripheral quantitative CT scan twice during 8 months - take study pills for 4-6 weeks at the beginning of the study to ensure safety - take either potassium citrate or placebo for 6 months during the blinded portion of the study Researchers will compare the bone imaging between the potassium citrate and the placebo groups at the end of the study.

NCT ID: NCT05843825 Completed - Bone Loss Clinical Trials

Effect of Block-out Spacer to Pick up Locator Attachments to Retain Overdenture: Peri-implant and Alveolar Bone Changes

Start date: January 20, 2021
Phase: N/A
Study type: Interventional

This study was conducted to radiographically evaluate peri-implant and alveolar bone height changes of locator attachments used for three implant assisted mandibular complete overdenture using two different pick up protocols.

NCT ID: NCT05843331 Completed - Bone Loss Clinical Trials

Vertical Versus Inclined Implant to Retain Locator Maxillary Overdenture

Start date: January 15, 2022
Phase: N/A
Study type: Interventional

Objectives: evaluate the success rate, prosthetic maintenance , clinical and radiologic results of vertical implants with straight abutments versus inclined implants with angled abutments to retain locator maxillary overdentures. There were two groups : 1) The control group 2) The study group

NCT ID: NCT05804604 Completed - Bone Loss Clinical Trials

Bone Intake Proteins and Muscle Mass Deficiency in Proximal Femur Fractures

Start date: May 7, 2022
Phase:
Study type: Observational

The aim of this clinical trial is to compare serum concentration of bone intake proteins [ sex hormone-binding globulin (SHBG), cross linked C-telopeptide of type I collagen (CTX-I)] and muscle atrophy marker [creatine kinase (CK-MB)] between patients after the fracture of proximal femur and their age corresponding counterpart without the fracture. The main question it aims to answer is: • Is the higher concentration of bone intake proteins and muscle atrophy marker a predictive factor of proximal femur fracture? The part of participants (Group 1) will be hospitalized at the Department of Orthopaedics and Rehabilitation and will undergo a surgical treatment (open reduction of the fracture). The rest (Group 2) will be admitted to the Department of Internal Medicine. Participants of both Groups will have the blood sample test taken, to evaluate and compare the serum concentration of SHBG, CTX-I and CK-MB proteins.