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Bone Loss clinical trials

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NCT ID: NCT05843331 Completed - Bone Loss Clinical Trials

Vertical Versus Inclined Implant to Retain Locator Maxillary Overdenture

Start date: January 15, 2022
Phase: N/A
Study type: Interventional

Objectives: evaluate the success rate, prosthetic maintenance , clinical and radiologic results of vertical implants with straight abutments versus inclined implants with angled abutments to retain locator maxillary overdentures. There were two groups : 1) The control group 2) The study group

NCT ID: NCT05804604 Completed - Bone Loss Clinical Trials

Bone Intake Proteins and Muscle Mass Deficiency in Proximal Femur Fractures

Start date: May 7, 2022
Phase:
Study type: Observational

The aim of this clinical trial is to compare serum concentration of bone intake proteins [ sex hormone-binding globulin (SHBG), cross linked C-telopeptide of type I collagen (CTX-I)] and muscle atrophy marker [creatine kinase (CK-MB)] between patients after the fracture of proximal femur and their age corresponding counterpart without the fracture. The main question it aims to answer is: • Is the higher concentration of bone intake proteins and muscle atrophy marker a predictive factor of proximal femur fracture? The part of participants (Group 1) will be hospitalized at the Department of Orthopaedics and Rehabilitation and will undergo a surgical treatment (open reduction of the fracture). The rest (Group 2) will be admitted to the Department of Internal Medicine. Participants of both Groups will have the blood sample test taken, to evaluate and compare the serum concentration of SHBG, CTX-I and CK-MB proteins.

NCT ID: NCT05764733 Recruiting - Bone Loss Clinical Trials

Bone, Exercise, Alendronate, and Caloric Restriction

BEACON
Start date: June 8, 2023
Phase: Phase 3
Study type: Interventional

The purpose of this research is to identify strategies that minimize bone loss that occurs when older adults lose weight. Participation in this research will involve up to nine assessment visits and last up to two years.

NCT ID: NCT05721014 Completed - Osteoporosis Clinical Trials

Effects of OsteoStrong vs. Individually Adapted and Combined Training on Bone Health

Start date: October 4, 2021
Phase: N/A
Study type: Interventional

The aim of this clinical trial is to investigate the effect of the OsteoStrong training method and the Individually Adapted and Combined Training on the bone health of older women with high fracture risk. Additionally, the aim is also to explore the participants' experiences of each training method. Participants will be randomised to either treatment arm A (OsteoStrong) or treatment arm B (Individually Adapted and Combined Training). Participants in both groups will train for nine months. Treatment arm A will train individually once a week and treatment arm B will train in a group twice a week. Both groups will have a training instructor who will supervise and give training instructions. Researchers will compare the groups to see the effects of the training methods on the participants' bone health among other outcome measures. The participants will be tested at baseline and post-intervention (9 months later).

NCT ID: NCT05710497 Completed - Bone Loss Clinical Trials

Maxillary Vascular Canal Thickness and Sinus Augmentation Bleeding

Start date: March 1, 2023
Phase:
Study type: Observational

This study aims to evaluate the relationship between the maxillary intra-osseous vascular canal thickness as measured by volumetric tomography and the amount of intra-operative bleeding during open sinus floor augmentation. A sample of patients will be selected, and their maxillary intra-osseous vascular canal thickness will be measured using volumetric tomography. Intraoperative bleeding will be recorded during open sinus floor augmentation. The data will be analyzed to determine if there is a correlation between the thickness of the maxillary intra-osseous vascular canal and intraoperative bleeding.

NCT ID: NCT05701254 Recruiting - Type 1 Diabetes Clinical Trials

Skeletal Effects of Type 1 Diabetes on Low-Trauma Fracture Risk

Start date: June 18, 2019
Phase:
Study type: Observational

Patients with Type 1 Diabetes Mellitus (T1DM) have a higher risk of low-trauma (osteoporotic) fracture that is 7-12 times higher than non-diabetics. The bone density of people with Type 1 Diabetes is higher at the time of fracture than in non-diabetics. This suggests the presence of underlying bone tissue mechanical defects. The potential benefits to participants would be knowledge gained about their bone density and the results of laboratory tests. On a wider scale, there may be general benefits to society because the knowledge gained from this study may help better understand the effects of diabetes on bone health

NCT ID: NCT05670340 Completed - Bone Loss Clinical Trials

Effect of Bone-related and Soft-tissue-related Variables on the Marginal Bone Loss of Platform-matched and Platform Switched Dental Implants

Start date: January 22, 2020
Phase: N/A
Study type: Interventional

In this clinical trial the effect of the implant-abutment morphology (platform-switched vs platform matched) will be assessed in both soft tissue (soft tissue thickness) and hard tissue (marginal bone loss) outcomes. Several clinical predictors (initial implant position level, gingival biotype, abutment height and prosthetic emergence profile) will also be taken into account as modulating factors of the clinical outcome.

NCT ID: NCT05666414 Completed - Bone Loss Clinical Trials

Vertical Bone Gain and Neurosensory Affection in Computer Guided vs Conventional Sandwich Osteotomy

Start date: November 25, 2021
Phase: N/A
Study type: Interventional

The aim of this study was to assess the efficiency of the computer-guided interpositional sandwich osteotomy for the vertical bone gain and effects on vital structures (inferior dental nerve bundle) compared to free hand interpositional osteotomies.

NCT ID: NCT05658419 Completed - Bone Loss Clinical Trials

Immediate Implant vs.Socket Shield Technique in Esthetic Zone

Implants
Start date: January 14, 2021
Phase: N/A
Study type: Interventional

immediate implant placement versus socket shield approach

NCT ID: NCT05658289 Recruiting - Bone Loss Clinical Trials

Latarjet vs Anatomic Glenoid Reconstruction

Start date: April 24, 2023
Phase: N/A
Study type: Interventional

Anterior shoulder dislocations occur when the humeral head translates anterior to the glenoid cause pain, stiffness, and glenoid bone loss. If left untreated, the risk of recurrence can be up to or greater than 90%. The only surgically modifiable factor to reduce the risk of recurrence is the glenoid bone loss (GBL), where surgeons have the ability to recreate the shape of the glenoid and reduce the risk of recurrent shoulder dislocations. Established boney procedures for shoulder instability include the Latarjet and free bone block procedures, such as the Anatomic Glenoid Reconstruction (AGR). The Latarjet is well known for its lower rate of recurrent instability, but raises concerns due to under-appreciated complications rates. The AGR is a newer surgical approach that has garnered attention for its low rate of recurrent instability and complication profile. Both treatments can reduce pain, increase function following surgery and reduce the risk of recurrent instability. However, these two established approaches have yet to be directly compared and studied on a larger scale. The purpose of this randomized control trial is to compare clinical and radiographic outcomes pre- and post-operatively between the Latarjet to the AGR.