The Effects of a Jump Rope Exercise Program on Vascular Health, Inflammatory Markers in Prehypertensive Adolescent Girls

Blood Pressure Clinical Trial

Official title:

The Effects of a 12-Week Jump Rope Exercise Training Program on Arterial Stiffness, Vasodilating and Vasoconstricting Factors, Inflammatory Markers, and Body Composition in Prehypertensive Adolescent Girls

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03534427
• Other study ID #: PusanNU1
• Status: Completed
• Phase: N/A
• Start date: June 5, 2011
• Est. completion date: March 21, 2012

Study information

• Verified date: October 2020
• Source: Pusan National University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study was to examine the impact of a 12-week jump rope exercise program on blood pressure, arterial stiffness, vasodilating and vasoconstricting factors, inflammatory markers, and body composition in prehypertensive adolescent girls. Forty prehypertensive adolescent girls participated in this study. The girls were randomly divided into the jump rope exercise intervention group (EX, n=20) and control group (CON, n=20). The EX group performed a jump rope training program at 40-70% of their heart rate reserve (HRR) 5 days/week for 12 weeks (sessions 50 minutes in duration). The CON group did not participate in any structured or unstructured exercise protocol. Blood pressure, arterial stiffness, plasma nitrate/nitrite levels, endothelin-1, C-reactive protein, and body composition were measured before and after the 12-weeks study.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 40
• Est. completion date: March 21, 2012
• Est. primary completion date: February 10, 2012
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 14 Years to 16 Years

Eligibility

Inclusion Criteria:

• prehypertensive
• sedentary (no regular exercise training or physical activity within the last year)
• no weight loss diet during the last six months

Exclusion Criteria:

• pregnancy
• chronic disease
• daily medication use (including antioxidants and weight loss supplements)

Related Conditions & MeSH terms

• Abdominal Obesity
• Adiposity
• Blood Pressure
• Obesity
• Obesity, Abdominal
• Prehypertension

Intervention

Other:
• Jump rope exercise intervention
12-week jump rope exercise program

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Pusan National University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Arterial Stiffness	Arterial stiffness was measured as measurement of brachial to ankle pulse-wave velocity. This indicates peripheral arterial stiffness, as it measures how quickly a pulse wave propagates from one point to another.	12 weeks
Primary	Endothelin-1	Levels of Endothelin-1 in blood were measured by Endothelin-1 enzyme immunoassay kit.	12 weeks
Primary	Body Mass	Body mass was measured to nearest 0.1 kg.	12 weeks
Primary	Height	Height was measured to nearest 1 cm.	12 weeks
Primary	Waist Circumference	Waist circumference was measured at midpoint between the lower rib and the iliac crest at the end of a normal expiration using a tape measure.	12 weeks
Primary	Body Fat	Percent body fat (%) was determined using a bioelectrical impedance-meter.	12 weeks
Primary	Lean Body Mass	Lean body mass (kg) was determined using a bioelectrical impedance-meter.	12 weeks
Primary	Nitrate/Nitrite Levels	Nitrate and nitrite levels were assayed using a Griess assay kit.	12 weeks
Primary	C-reactive Protein	C-reactive protein was assessed using an enzyme immunoassay assay kit	12 weeks
Primary	Systolic Blood Pressure	Blood pressure was measured in duplicate using an automated sphygmomanometer. The average of the two was recorded as the resting blood pressure.	12 weeks
Primary	Diastolic Blood Pressure		12 weeks