Blood Pressure Clinical Trial
Official title:
Influence of Dietary Nitrate Supplementation on Blood Pressure, Walking Economy, Functional Physical Capacity and Cognitive Function in Healthy Older Adults
Verified date | March 2018 |
Source | University of Exeter |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This study investigates the influence of dietary nitrate supplementation on cardiovascular health and physical and cognitive performance in older adults. Participants will receive both a nitrate containing beetroot juice for 10 days and a nitrate depleted beetroot juice for 10 days
Status | Completed |
Enrollment | 30 |
Est. completion date | January 2018 |
Est. primary completion date | May 28, 2015 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 70 Years to 80 Years |
Eligibility |
Inclusion Criteria: 1. 70 - 80 years of age 2. male or female Exclusion Criteria: 1. involved in regular structured exercise 2. receiving medication for: - pulmonary conditions - cardiovascular conditions - metabolic conditions - musculoskeletal conditions - ulcerative colitis - renal disease |
Country | Name | City | State |
---|---|---|---|
United Kingdom | Sport and Health Sciences, University of Exeter | Exeter | Devon |
Lead Sponsor | Collaborator |
---|---|
University of Exeter |
United Kingdom,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Blood pressure | Change in blood pressure between interventions | 10 days | |
Secondary | Oxygen cost of exercise | Change in oxygen consumption during exercise | 10 days | |
Secondary | Serial Subtraction test | change in performance of the Serial Subtraction test | 10 days | |
Secondary | Microbiome | change in oral microbiome measured by sequencing bacterial 16S rRNA genes | 10 days | |
Secondary | Brain metabolism | change in brain metabolites measured measured by 1H MRS | 10 days | |
Secondary | 6 minute walk test | change in performance of 6 minute walk test | 10 days |
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